April 20 has come and gone, but ASX cannabis companies aren’t getting that high — they’re actually low.

Of the 36 pot companies in the space, 27 have lost ground over the last fortnight. Just seven have advanced.

Gains were led by Wide Open Agriculture (ASX:WOA), which was up 28.3 per cent to 93c — and nearly sevenfold from a year ago — as it works to commercialise plant-based proteins, foods and beverages.

Incannex Healthcare (ASX:IHL) was the second-biggest gainer in the period from April 8 to April 22, up 27.9 per cent to 27.5c following a positive meeting with the US Food and Drug Administration about its plans for its cannabis-based drug candidate IHL-675A, which it hopes to register as a treatment for lung inflammation, irritable bowel disease and rheumatoid arthritis.

IDT Australia (ASX:IDT) rose 12.3 per cent during the fortnight to 41c, as the market awaits word on whether the pharmaceutical company will be asked to help produce the AstraZeneca COVID-19 vaccine.

On the flip side, Medlab Clinical (ASX:MDC) was the biggest loser, falling 20.8 per cent despite making progress on its NanaBis observational study on using cannabis to treat cancer-induced bone pain.

DTZ Dotz Nano 35.5 -2.7
SUD Suda Pharmaceuticals 4.3 -6.5
IHL Incannex Healthcare 27.5 27.9
RNO Rhinomed 12 -4.0
EOF Ecofibre 108 -9.2
LV1 Live Verdure 22.5 -10.0
LSH Lifespot Health 10.5 0.0
AC8 Auscann 13 -3.7
PAL Palla Pharma 44.5 -8.2
EXL Elixinol Global 17 -8.1
LGP Little Green Pharma 75.5 4.1
MXC Mgc Pharmaceuticals 6.2 -11.4
MDC Medlab Clinical 21 -20.8
ROO Roots Sustainable 1.7 -10.5
WOA Wide Open Agricultur 93 28.3
CGB Cann Global 0.75 -6.3
MRG Murray River Grp 26.5 8.2
NTI Neurotech Intl 6.1 -19.7
APH AP Hemp 43.5 6.1
IDT IDT Australia 41 12.3
RGI Roto-Gro Intl 4.8 -2.0
EN1 Engage:Bdr 0.55 -8.3
CPH Creso Pharma 19 -7.3
ECS ECS Botanics Holding 4.8 -5.9
MMJ MMJ Group Hlds 10.5 -4.5
ZLD Zelira Therapeutics 5.8 -4.9
CAN Cann Group 50 -9.1
AGH Althea Group 48.5 -4.9
BOT Botanix Pharma 8.7 -6.5
ESE Esense-Lab 1.8 0.0
EPN Epsilon Healthcare 17.5 -18.6
SCU Stemcell United 1.9 -13.6
BDA Bod Australia 47 -10.5
CAU Cronos Australia 13 8.3
YPB YPB Group 0.3 -14.3
EVE EVE Investments 0.65 -7.1
Code Name Price Fortnight % return

Elsewhere in the cannabis space, the blockbuster merger between Canadian cannabis giants Aphria (TSE:APHA) and Tilray (NASDAQ:TLRY) moved a step closer last week after the latter company made a significant revision to its corporate bylaws.

In the United States, Virginia became the first southern state to legalise recreational marijuana and the 16h state overall.