Here’s our monthly wrap of all the news driving ASX small cap health stocks.

This might not make initial sense, but the biggest winner in small cap health and biotech land at the moment? Factor Therapeutics (ASX:FTT).

Factor is the company which lost 97 per cent of its value last year when its venous leg ulcer trial failed to show any improvement over standard of care.

Dr Rosalind Wilson, who resigned as Factor’s CEO in January but continues to work with the company in an advisory capacity as it seeks to find a new opportunity, recently told Stockhead the trial could not be considered a failure as it had produced unambiguous results that provided “a clear basis for decision-making”. Unfortunately for all involved, that decision was to cease all research and development and scale the company down.

But its shares are up 80 per cent since we last checked in on the 140-odd small cap healthcare stocks.

On the one hand, that’s not hard, given FTT shares have been trading two-tenths of a cent and half a cent since November.

But there have been rumblings behind the movement, too: it raised $417,000 in capital and also fought off a 249d notice that would have seen three of its directors ousted.

Bionomics (ASX:BNO), another company that had a busted clinical trial last year, is also a big winner, with shares up 54 per cent to 20c.

That is because the company has been telling investors that its PTSD drug might work after all.

A spokesman for the company said the original trial included people who didn’t take the drug properly — with food — and later analysis showed that among those who did take the drug correctly, it remained in the patients’ bloodstream and did have a positive effect on PTSD symptoms.

Pot stock Althea (ASX:AGH) is up 46 per cent in the past month as it has expanded into the UK, sponsored a medicinal cannabis education portal and signed a supply and distribution agreement with Cannvalate, a network of clinicians who can prescribe medicinal cannabis.

CEO Josh Fegan recently told Stockhead that it would be growing enough marijuana to start commercial sales in the next 18 months.

Meanwhile, Matt Callahan, CEO of Botanix (ASX:BOT) — a company trialling synthetically-derived cannabidiol (CBD) treatment for acne, psoriasis and dermatitis but not one that considers itself a cannabis company — recently told Stockhead that synthetics are the future of cannabis drugs.

His company’s shares are up 15 per cent in the past month to 11c, as it nears data collection from a couple of Phase 2 trials.

The common factor for the biggest losers in the past month is they have all reported financial results that have been met with skepticism from investors.

Allegra Orthopaedics (ASX:AMT) is the worst of the lot, losing nearly half of its value, falling to 10.5c. Money-making lens manufacturer Visioneering Technologies (ASX:VTI) has fallen 39 per cent to 9.9c thanks to a full-year bottom line that barely moved on the previous year.

AusCann (ASX:AC8) has also suffered a fall, shares dropping 33 per cent to 44c in the past month.

It has finally appointed a new CEO, five months after the company began its search:  Ido Kanyon, currently Israeli firm Teva Pharmaceutical’s global head of specialty products, will start at the end of May.

Here’s a table showing price performance for the ASX’s small cap health stocks since mid-November.

Swipe or scroll to reveal full table. Click headings to sort

ASX codeCompanyLast priceMarket cap1-mnth return
AMT ALLEGRA ORTHOPAEDICS LTD0.105 $10,453,700.00 -48
VTI VISIONEERING TECH-CDI0.099 $25,245,368.00 -39
DVL DORSAVI LTD0.04 $8,568,705.00 -38
ADR ADHERIUM LTD0.023 $4,182,574.25 -34
AC8 AUSCANN GROUP HOLDINGS LTD0.44 $131,363,184.00 -33
RGS REGENEUS LTD0.105 $22,977,366.00 -32
BIT BIOTRON LTD0.075 $41,085,988.00 -32
NTI NEUROTECH INTERNATIONAL LTD0.028 $3,529,340.50 -29
IBX IMAGION BIOSYSTEMS LTD0.027 $8,068,570.50 -29
IVQINVITROCUE LTD0.075$38,500,000-29
ATX AMPLIA THERAPEUTICS LTD0.12 $5,127,913.00 -25
KKT KONEKT LTD0.215 $22,701,170.00 -25
LSH LIFESPOT HEALTH LTD0.068 $5,429,807.50 -24
OSP OSPREY MEDICAL INC-CDI0.105 $49,656,696.00 -23
BD1 BARD1 LIFE SCIENCES LTD0.017 $17,899,114.00 -23
CAN CANN GROUP LTD1.74 $243,783,904.00 -22
FFC FARMAFORCE LTD0.095 $12,141,093.00 -21
ESE ESENSE-LAB LTD-CDI0.023 $4,270,569.00 -21
CPH CRESO PHARMA LTD0.39 $52,160,288.00 -20
SUD SUDA PHARMACEUTICALS LTD0.005 $11,618,816.00 -20
PGC PARAGON CARE LTD0.47 $158,449,568.00 -19
TPE TPI ENTERPRISES LTD0.95 $77,031,312.00 -19
RNO RHINOMED LTD0.155 $21,999,658.00 -18
LCT LIVING CELL TECHNOLOGIES LTD0.038 $22,286,198.00 -18
CGS COGSTATE LTD0.305 $56,618,192.00 -17
MEM MEMPHASYS LTD0.027 $9,466,318.00 -16
VHT VOLPARA HEALTH TECHNOLOGIES1.065 $190,111,168.00 -16
NC6 NANOLLOSE LTD0.084 $6,224,999.50 -16
IMU IMUGENE LTD0.017 $57,757,540.00 -16
ACR ACRUX LTD0.165 $27,482,188.00 -15
GLH GLOBAL HEALTH LTD0.145 $4,883,396.00 -15
RAP RESAPP HEALTH LTD0.086 $63,768,008.00 -14
ANR ANATARA LIFESCIENCES LTD0.39 $19,765,294.00 -13
VLS VITA LIFE SCIENCES LTD0.865 $47,164,340.00 -13
BXN BIOXYNE LTD0.022 $13,443,053.00 -12
CP1 CANNPAL ANIMAL THERAPEUTICS0.11 $10,709,375.00 -12
1AD ADALTA LTD0.24 $28,225,086.00 -11
IVX INVION LTD0.016 $82,509,096.00 -11
NEU NEUREN PHARMACEUTICALS LTD1.18 $124,835,728.00 -11
MDC MEDLAB CLINICAL LTD0.38 $78,008,128.00 -11
PYC PHYLOGICA LTD0.026 $61,071,416.00 -11
RVA REVA MEDICAL INC - CDI0.17 $70,561,504.00 -11
SVA SIMAVITA LTD-CDI0.017 $7,102,228.00 -11
RHT RESONANCE HEALTH LTD0.078 $31,394,810.00 -10
ACL ALCHEMIA LTD0.009 $2,922,512.50 -10
ALT ANALYTICA LTD0.0045 $15,016,556.00 -10
ANP ANTISENSE THERAPEUTICS LTD0.038 $13,006,652.00 -10
LBT LBT INNOVATIONS LTD0.071 $14,868,600.00 -10
CTE CRYOSITE LTD0.041 $1,921,242.13 -9
PAB PATRYS LTD0.021 $22,524,396.00 -9
ONE ONEVIEW HEALTHCARE PLC-CDI0.5 $35,084,308.00 -8
NHL NOVITA HEALTHCARE LTD0.024 $11,681,934.00 -7
HLA HEALTHIA LTD1 $63,034,656.00 -7
PAR PARADIGM BIOPHARMACEUTICALS1.12 $159,941,360.00 -7
UBI UNIVERSAL BIOSENSORS INC-CDI0.225 $37,221,140.00 -7
RCE RECCE PHARMACEUTICALS LTD0.145 $16,069,488.00 -6
CAJ CAPITOL HEALTH LTD0.18 $188,536,544.00 -6
CYC CYCLOPHARM LTD1.185 $81,408,168.00 -6
PAA PHARMAUST LTD0.034 $6,970,463.00 -6
RSH RESPIRI LTD0.08 $43,122,416.00 -6
OSL ONCOSIL MEDICAL LTD0.175 $110,374,040.00 -6
PTX PRESCIENT THERAPEUTICS LTD0.066 $15,043,697.00 -6
DXB DIMERIX LTD0.085 $13,815,551.00 -5
IHL IMPRESSION HEALTHCARE LTD0.017 $9,805,686.00 -5
PSQ PACIFIC SMILES GROUP LTD1.3 $193,031,616.00 -5
TLX TELIX PHARMACEUTICALS LTD0.7 $157,223,408.00 -5
ELX ELLEX MEDICAL LASERS LTD0.585 $81,852,624.00 -4
ZLD ZELDA THERAPEUTICS LTD0.053 $40,788,464.00 -4
AZV AZURE HEALTHCARE LTD0.055 $12,799,205.00 -4
OVN OVENTUS MEDICAL LTD0.29 $31,781,764.00 -3
OPT OPTHEA LTD0.74 $190,802,352.00 -3
MXC MGC PHARMACEUTICALS LTD0.039 $48,513,216.00 -3
SCU STEMCELL UNITED LTD0.021 $10,822,249.00 -2
ALC ALCIDION GROUP LTD0.042 $37,060,872.00 -2
MMJ MMJ GROUP HOLDINGS LTD0.25 $55,235,756.00 -2
VBS VECTUS BIOSYSTEMS LTD0.36 $8,533,699.00 -1
ONT 1300 SMILES LTD6.17 $146,569,200.00 -1
RAC RACE ONCOLOGY LTD0.082 $7,236,751.50 -1
PBP PROBIOTEC LTD1.51 $96,701,472.00 0
BPH BPH ENERGY LTD0.001 $2,543,277.75 0
CMP COMPUMEDICS LTD0.36 $60,235,404.00 0
GTG GENETIC TECHNOLOGIES LTD0.008 $21,152,926.00 0
ICS ICSGLOBAL LTD0.95 $10,054,818.00 0
IMC IMMURON LTD0.26 $37,952,164.00 0
IMM IMMUTEP LTD0.03 $101,507,952.00 0
KZA KAZIA THERAPEUTICS LTD0.49 $30,772,504.00 0
M7T MACH7 TECHNOLOGIES LTD0.195 $29,493,632.00 0
MEB MEDIBIO LTD0.018 $3,849,937.25 0
MGZ MEDIGARD LTD0.02 $2,706,006.50 0
OBJ OBJ LTD0.021 $36,189,252.00 0
POH PHOSPHAGENICS LTD0.004 $5,521,101.00 0
RHY RHYTHM BIOSCIENCES LTD0.135 $14,105,000.00 0
SDX SIENNA CANCER DIAGNOSTICS LT0.064 $17,380,312.00 0
SIL SMILES INCLUSIVE LTD0.29 $16,800,540.00 0
TDL TBG DIAGNOSTICS LTD0.041 $8,921,079.00 0
UCM USCOM LTD0.12 $17,205,108.00 0
JHC JAPARA HEALTHCARE LTD1.24 $336,590,432.00 2
GMV G MEDICAL INNOVATION HOLDING0.29 $106,745,136.00 2
ACW ACTINOGEN MEDICAL LTD0.054 $60,368,952.00 2
MX1 MICRO-X LTD0.27 $31,110,410.00 2
AHX APIAM ANIMAL HEALTH LTD0.48 $52,637,372.00 2
EHH EAGLE HEALTH HOLDINGS LTD0.215 $68,462,416.00 2
SOM SOMNOMED LTD1.71 $109,593,272.00 3
IDT IDT AUSTRALIA LTD0.16 $36,727,740.00 3
OCC ORTHOCELL LTD0.135 $16,303,921.00 4
CDY CELLMID LTD0.265 $22,288,776.00 4
PXS PHARMAXIS LTD0.265 $106,458,648.00 4
MVP MEDICAL DEVELOPMENTS INTERNA4.26 $248,527,376.00 4
SKN SKIN ELEMENTS LTD0.021 $2,597,986.50 5
ADO ANTEO DIAGNOSTICS LTD0.019 $20,875,618.00 6
MVF MONASH IVF GROUP LTD1 $230,869,328.00 6
ITD ITL HEALTH GROUP LTD0.145 $10,293,451.00 7
THC THC GLOBAL GROUP LTD0.5 $64,911,560.00 7
NOX NOXOPHARM LTD0.43 $54,364,212.00 9
PIQ PROTEOMICS INTERNATIONAL LAB0.34 $27,374,068.00 10
CYP CYNATA THERAPEUTICS LTD1.55 $151,735,104.00 10
EXL ELIXINOL GLOBAL LTD3.48 $414,752,032.00 10
MDR MEDADVISOR LTD0.041 $58,502,128.00 11
S66 STAR COMBO PHARMA LTD0.61 $52,354,644.00 11
JHL JAYEX HEALTHCARE LTD0.03 $4,693,164.50 11
1ST 1ST GROUP LTD0.03 $7,059,248.00 12
CDX CARDIEX LTD0.061 $38,500,280.00 13
PCK PAINCHEK LTD0.04 $33,515,384.00 14
PBT PRANA BIOTECHNOLOGY LTD0.04 $22,741,750.00 14
PNV POLYNOVO LTD0.76 $485,899,712.00 15
BOT BOTANIX PHARMACEUTICALS LTD0.11 $87,103,832.00 15
NVL NATIONAL VETERINARY CARE LTD2.1 $135,342,752.00 21
NSB NEUROSCIENTIFIC BIOPHARMACEU0.2 $15,084,021.00 21
AVH AVITA MEDICAL LTD0.14 $251,699,344.00 22
GSS GENETIC SIGNATURES LTD0.94 $98,825,592.00 25
AXP AIRXPANDERS INC-CDI0.039 $21,779,934.00 25
BLT BENITEC BIOPHARMA LTD0.135 $30,843,532.00 27
SDI SDI LTD0.84 $100,441,376.00 27
OIL OPTISCAN IMAGING LTD0.058 $26,393,406.00 29
IPD IMPEDIMED LTD0.245 $96,722,600.00 29
BWX BWX LTD2.29 $288,259,744.00 38
HCT HOLISTA COLLTECH LTD0.063 $14,744,462.00 43
AGH ALTHEA GROUP HOLDINGS LTD0.435 $85,390,200.00 46
BNO BIONOMICS LTD0.2 $106,213,744.00 54
FTT FACTOR THERAPEUTICS LTD0.005 $3,128,507.00 80
SILSMILES INCLUSIVE0.545
RAPRESAPP HEALTH0.105
AXPAIRXPANDERS-CDI0.04