Here’s our monthly wrap of all the news driving ASX small cap health stocks.

This might not make initial sense, but the biggest winner in small cap health and biotech land at the moment? Factor Therapeutics (ASX:FTT).

Factor is the company which lost 97 per cent of its value last year when its venous leg ulcer trial failed to show any improvement over standard of care.

Dr Rosalind Wilson, who resigned as Factor’s CEO in January but continues to work with the company in an advisory capacity as it seeks to find a new opportunity, recently told Stockhead the trial could not be considered a failure as it had produced unambiguous results that provided “a clear basis for decision-making”. Unfortunately for all involved, that decision was to cease all research and development and scale the company down.

But its shares are up 80 per cent since we last checked in on the 140-odd small cap healthcare stocks.

On the one hand, that’s not hard, given FTT shares have been trading two-tenths of a cent and half a cent since November.

But there have been rumblings behind the movement, too: it raised $417,000 in capital and also fought off a 249d notice that would have seen three of its directors ousted.

Bionomics (ASX:BNO), another company that had a busted clinical trial last year, is also a big winner, with shares up 54 per cent to 20c.

That is because the company has been telling investors that its PTSD drug might work after all.

A spokesman for the company said the original trial included people who didn’t take the drug properly — with food — and later analysis showed that among those who did take the drug correctly, it remained in the patients’ bloodstream and did have a positive effect on PTSD symptoms.

Pot stock Althea (ASX:AGH) is up 46 per cent in the past month as it has expanded into the UK, sponsored a medicinal cannabis education portal and signed a supply and distribution agreement with Cannvalate, a network of clinicians who can prescribe medicinal cannabis.

CEO Josh Fegan recently told Stockhead that it would be growing enough marijuana to start commercial sales in the next 18 months.

Meanwhile, Matt Callahan, CEO of Botanix (ASX:BOT) — a company trialling synthetically-derived cannabidiol (CBD) treatment for acne, psoriasis and dermatitis but not one that considers itself a cannabis company — recently told Stockhead that synthetics are the future of cannabis drugs.

His company’s shares are up 15 per cent in the past month to 11c, as it nears data collection from a couple of Phase 2 trials.

The common factor for the biggest losers in the past month is they have all reported financial results that have been met with skepticism from investors.

Allegra Orthopaedics (ASX:AMT) is the worst of the lot, losing nearly half of its value, falling to 10.5c. Money-making lens manufacturer Visioneering Technologies (ASX:VTI) has fallen 39 per cent to 9.9c thanks to a full-year bottom line that barely moved on the previous year.

AusCann (ASX:AC8) has also suffered a fall, shares dropping 33 per cent to 44c in the past month.

It has finally appointed a new CEO, five months after the company began its search:  Ido Kanyon, currently Israeli firm Teva Pharmaceutical’s global head of specialty products, will start at the end of May.

Here’s a table showing price performance for the ASX’s small cap health stocks since mid-November.

Swipe or scroll to reveal full table. Click headings to sort

ASX code Company Last price Market cap 1-mnth return
AMT ALLEGRA ORTHOPAEDICS LTD 0.105 $10,453,700.00 -48
VTI VISIONEERING TECH-CDI 0.099 $25,245,368.00 -39
DVL DORSAVI LTD 0.04 $8,568,705.00 -38
ADR ADHERIUM LTD 0.023 $4,182,574.25 -34
AC8 AUSCANN GROUP HOLDINGS LTD 0.44 $131,363,184.00 -33
RGS REGENEUS LTD 0.105 $22,977,366.00 -32
BIT BIOTRON LTD 0.075 $41,085,988.00 -32
NTI NEUROTECH INTERNATIONAL LTD 0.028 $3,529,340.50 -29
IBX IMAGION BIOSYSTEMS LTD 0.027 $8,068,570.50 -29
IVQ INVITROCUE LTD 0.075 $38,500,000 -29
ATX AMPLIA THERAPEUTICS LTD 0.12 $5,127,913.00 -25
KKT KONEKT LTD 0.215 $22,701,170.00 -25
LSH LIFESPOT HEALTH LTD 0.068 $5,429,807.50 -24
OSP OSPREY MEDICAL INC-CDI 0.105 $49,656,696.00 -23
BD1 BARD1 LIFE SCIENCES LTD 0.017 $17,899,114.00 -23
CAN CANN GROUP LTD 1.74 $243,783,904.00 -22
FFC FARMAFORCE LTD 0.095 $12,141,093.00 -21
ESE ESENSE-LAB LTD-CDI 0.023 $4,270,569.00 -21
CPH CRESO PHARMA LTD 0.39 $52,160,288.00 -20
SUD SUDA PHARMACEUTICALS LTD 0.005 $11,618,816.00 -20
PGC PARAGON CARE LTD 0.47 $158,449,568.00 -19
TPE TPI ENTERPRISES LTD 0.95 $77,031,312.00 -19
RNO RHINOMED LTD 0.155 $21,999,658.00 -18
LCT LIVING CELL TECHNOLOGIES LTD 0.038 $22,286,198.00 -18
CGS COGSTATE LTD 0.305 $56,618,192.00 -17
MEM MEMPHASYS LTD 0.027 $9,466,318.00 -16
VHT VOLPARA HEALTH TECHNOLOGIES 1.065 $190,111,168.00 -16
NC6 NANOLLOSE LTD 0.084 $6,224,999.50 -16
IMU IMUGENE LTD 0.017 $57,757,540.00 -16
ACR ACRUX LTD 0.165 $27,482,188.00 -15
GLH GLOBAL HEALTH LTD 0.145 $4,883,396.00 -15
RAP RESAPP HEALTH LTD 0.086 $63,768,008.00 -14
ANR ANATARA LIFESCIENCES LTD 0.39 $19,765,294.00 -13
VLS VITA LIFE SCIENCES LTD 0.865 $47,164,340.00 -13
BXN BIOXYNE LTD 0.022 $13,443,053.00 -12
CP1 CANNPAL ANIMAL THERAPEUTICS 0.11 $10,709,375.00 -12
1AD ADALTA LTD 0.24 $28,225,086.00 -11
IVX INVION LTD 0.016 $82,509,096.00 -11
NEU NEUREN PHARMACEUTICALS LTD 1.18 $124,835,728.00 -11
MDC MEDLAB CLINICAL LTD 0.38 $78,008,128.00 -11
PYC PHYLOGICA LTD 0.026 $61,071,416.00 -11
RVA REVA MEDICAL INC - CDI 0.17 $70,561,504.00 -11
SVA SIMAVITA LTD-CDI 0.017 $7,102,228.00 -11
RHT RESONANCE HEALTH LTD 0.078 $31,394,810.00 -10
ACL ALCHEMIA LTD 0.009 $2,922,512.50 -10
ALT ANALYTICA LTD 0.0045 $15,016,556.00 -10
ANP ANTISENSE THERAPEUTICS LTD 0.038 $13,006,652.00 -10
LBT LBT INNOVATIONS LTD 0.071 $14,868,600.00 -10
CTE CRYOSITE LTD 0.041 $1,921,242.13 -9
PAB PATRYS LTD 0.021 $22,524,396.00 -9
ONE ONEVIEW HEALTHCARE PLC-CDI 0.5 $35,084,308.00 -8
NHL NOVITA HEALTHCARE LTD 0.024 $11,681,934.00 -7
HLA HEALTHIA LTD 1 $63,034,656.00 -7
PAR PARADIGM BIOPHARMACEUTICALS 1.12 $159,941,360.00 -7
UBI UNIVERSAL BIOSENSORS INC-CDI 0.225 $37,221,140.00 -7
RCE RECCE PHARMACEUTICALS LTD 0.145 $16,069,488.00 -6
CAJ CAPITOL HEALTH LTD 0.18 $188,536,544.00 -6
CYC CYCLOPHARM LTD 1.185 $81,408,168.00 -6
PAA PHARMAUST LTD 0.034 $6,970,463.00 -6
RSH RESPIRI LTD 0.08 $43,122,416.00 -6
OSL ONCOSIL MEDICAL LTD 0.175 $110,374,040.00 -6
PTX PRESCIENT THERAPEUTICS LTD 0.066 $15,043,697.00 -6
DXB DIMERIX LTD 0.085 $13,815,551.00 -5
IHL IMPRESSION HEALTHCARE LTD 0.017 $9,805,686.00 -5
PSQ PACIFIC SMILES GROUP LTD 1.3 $193,031,616.00 -5
TLX TELIX PHARMACEUTICALS LTD 0.7 $157,223,408.00 -5
ELX ELLEX MEDICAL LASERS LTD 0.585 $81,852,624.00 -4
ZLD ZELDA THERAPEUTICS LTD 0.053 $40,788,464.00 -4
AZV AZURE HEALTHCARE LTD 0.055 $12,799,205.00 -4
OVN OVENTUS MEDICAL LTD 0.29 $31,781,764.00 -3
OPT OPTHEA LTD 0.74 $190,802,352.00 -3
MXC MGC PHARMACEUTICALS LTD 0.039 $48,513,216.00 -3
SCU STEMCELL UNITED LTD 0.021 $10,822,249.00 -2
ALC ALCIDION GROUP LTD 0.042 $37,060,872.00 -2
MMJ MMJ GROUP HOLDINGS LTD 0.25 $55,235,756.00 -2
VBS VECTUS BIOSYSTEMS LTD 0.36 $8,533,699.00 -1
ONT 1300 SMILES LTD 6.17 $146,569,200.00 -1
RAC RACE ONCOLOGY LTD 0.082 $7,236,751.50 -1
PBP PROBIOTEC LTD 1.51 $96,701,472.00 0
BPH BPH ENERGY LTD 0.001 $2,543,277.75 0
CMP COMPUMEDICS LTD 0.36 $60,235,404.00 0
GTG GENETIC TECHNOLOGIES LTD 0.008 $21,152,926.00 0
ICS ICSGLOBAL LTD 0.95 $10,054,818.00 0
IMC IMMURON LTD 0.26 $37,952,164.00 0
IMM IMMUTEP LTD 0.03 $101,507,952.00 0
KZA KAZIA THERAPEUTICS LTD 0.49 $30,772,504.00 0
M7T MACH7 TECHNOLOGIES LTD 0.195 $29,493,632.00 0
MEB MEDIBIO LTD 0.018 $3,849,937.25 0
MGZ MEDIGARD LTD 0.02 $2,706,006.50 0
OBJ OBJ LTD 0.021 $36,189,252.00 0
POH PHOSPHAGENICS LTD 0.004 $5,521,101.00 0
RHY RHYTHM BIOSCIENCES LTD 0.135 $14,105,000.00 0
SDX SIENNA CANCER DIAGNOSTICS LT 0.064 $17,380,312.00 0
SIL SMILES INCLUSIVE LTD 0.29 $16,800,540.00 0
TDL TBG DIAGNOSTICS LTD 0.041 $8,921,079.00 0
UCM USCOM LTD 0.12 $17,205,108.00 0
JHC JAPARA HEALTHCARE LTD 1.24 $336,590,432.00 2
GMV G MEDICAL INNOVATION HOLDING 0.29 $106,745,136.00 2
ACW ACTINOGEN MEDICAL LTD 0.054 $60,368,952.00 2
MX1 MICRO-X LTD 0.27 $31,110,410.00 2
AHX APIAM ANIMAL HEALTH LTD 0.48 $52,637,372.00 2
EHH EAGLE HEALTH HOLDINGS LTD 0.215 $68,462,416.00 2
SOM SOMNOMED LTD 1.71 $109,593,272.00 3
IDT IDT AUSTRALIA LTD 0.16 $36,727,740.00 3
OCC ORTHOCELL LTD 0.135 $16,303,921.00 4
CDY CELLMID LTD 0.265 $22,288,776.00 4
PXS PHARMAXIS LTD 0.265 $106,458,648.00 4
MVP MEDICAL DEVELOPMENTS INTERNA 4.26 $248,527,376.00 4
SKN SKIN ELEMENTS LTD 0.021 $2,597,986.50 5
ADO ANTEO DIAGNOSTICS LTD 0.019 $20,875,618.00 6
MVF MONASH IVF GROUP LTD 1 $230,869,328.00 6
ITD ITL HEALTH GROUP LTD 0.145 $10,293,451.00 7
THC THC GLOBAL GROUP LTD 0.5 $64,911,560.00 7
NOX NOXOPHARM LTD 0.43 $54,364,212.00 9
PIQ PROTEOMICS INTERNATIONAL LAB 0.34 $27,374,068.00 10
CYP CYNATA THERAPEUTICS LTD 1.55 $151,735,104.00 10
EXL ELIXINOL GLOBAL LTD 3.48 $414,752,032.00 10
MDR MEDADVISOR LTD 0.041 $58,502,128.00 11
S66 STAR COMBO PHARMA LTD 0.61 $52,354,644.00 11
JHL JAYEX HEALTHCARE LTD 0.03 $4,693,164.50 11
1ST 1ST GROUP LTD 0.03 $7,059,248.00 12
CDX CARDIEX LTD 0.061 $38,500,280.00 13
PCK PAINCHEK LTD 0.04 $33,515,384.00 14
PBT PRANA BIOTECHNOLOGY LTD 0.04 $22,741,750.00 14
PNV POLYNOVO LTD 0.76 $485,899,712.00 15
BOT BOTANIX PHARMACEUTICALS LTD 0.11 $87,103,832.00 15
NVL NATIONAL VETERINARY CARE LTD 2.1 $135,342,752.00 21
NSB NEUROSCIENTIFIC BIOPHARMACEU 0.2 $15,084,021.00 21
AVH AVITA MEDICAL LTD 0.14 $251,699,344.00 22
GSS GENETIC SIGNATURES LTD 0.94 $98,825,592.00 25
AXP AIRXPANDERS INC-CDI 0.039 $21,779,934.00 25
BLT BENITEC BIOPHARMA LTD 0.135 $30,843,532.00 27
SDI SDI LTD 0.84 $100,441,376.00 27
OIL OPTISCAN IMAGING LTD 0.058 $26,393,406.00 29
IPD IMPEDIMED LTD 0.245 $96,722,600.00 29
BWX BWX LTD 2.29 $288,259,744.00 38
HCT HOLISTA COLLTECH LTD 0.063 $14,744,462.00 43
AGH ALTHEA GROUP HOLDINGS LTD 0.435 $85,390,200.00 46
BNO BIONOMICS LTD 0.2 $106,213,744.00 54
FTT FACTOR THERAPEUTICS LTD 0.005 $3,128,507.00 80
SIL SMILES INCLUSIVE 0.545
RAP RESAPP HEALTH 0.105
AXP AIRXPANDERS-CDI 0.04