For all the investors that gain when their stock goes up several times, there are thousands more people wondering where they can make the same kind of gains.

Some will say it’s luck, others will say it’s some emerging industry that on one hand is visible enough to capture customers quickly through superior service; the other silent enough so competitors don’t even see the threat until it’s too late.

This week we’ve seen cell therapy play Orthocell (ASX: OCC) skyrocket from 9 cents to 51 cents in a single day – a 377 per cent gain. Why? The Phase III clinical trial of its CelGro technology found that it helps patients with damaged nerves regain sensation and muscle function.

We’ve also seen buy now pay later stock Splitit (ASX: SPT) surge from 20 cents to $2 in 6 weeks after its IPO. While it has now fallen back to $1, gaining five times your IPO price is still impressive.

But these still rank nowhere compared to the biggest gainers on the ASX in the last decade.

Stockhead analysis has found 43 stocks that in 10 years have gained 1000 per cent or more.

While we normally don’t cover large caps, ex-small caps gone big are an occasional exemption. Nevertheless, of these stocks, nearly a third of them still have market capitalisations of $500 million or under.

Patience pays off

The biggest gainer is Northern Star Resources (ASX: NST), which listed in 2003 and only raised $5 million at its IPO. In early 2009, in the immediate aftermath of the GFC, the company’s share price was under 2 cents and it only had $82,000 cash left.

But acquisitions of multiple gold projects and positive production figures have led to the company being one of the biggest resource explorers on the ASX with a market cap of $5 billion.

The one other stock that has gained over 10,000 per cent in 10 years only has a market cap of $543 million – Audio Pixels Holdings (ASX: AKP).

Unlike Northern Star, it has not had substantial revenue growth. Ten years ago it had only made $185,000 in the previous half year and in 2018 only made $89,961 in full year revenue.

However it has continued to develop loudspeakers and declared to investors earlier this year it was now “poised to revolutionise the loudspeaker market”.

Among the list you would find familiar names such as Dominos (ASX: DMP) and Webjet (ASX: WEB) whose stories tell themselves.

One notable member was online lottery business Jumbo Interactive (ASX: JIN). Its long term gains have allowed founder & CEO Mike Veverka to make $17.7 million from exercising lower priced options and then selling shares.

The bottom line from all this? Sometimes patience isn’t just a virtue, it can be a cash cow.

Code Name Price in May 2009 Price (8 May) Market Cap Return
NST NORTHERN STAR RESOURCES LTD 0.019 8.84 5582440960 447.3384
AKP AUDIO PIXELS HOLDINGS LTD 0.10 19.22 543959040 191.1
MFG MAGELLAN FINANCIAL GROUP LTD 0.44 44.53 7804244480 99.16
SMN STRUCTURAL MONITORING-CDI 0.07 0.84 96946168 11.45
JIN JUMBO INTERACTIVE LTD 0.24 16.29 992737664 66.91
ALU ALTIUM LTD 0.5 31.45 4130689792 61.9
AMA AMA GROUP LTD 0.019 1.19 649077440 61.63
MNF MNF GROUP LTD 0.09 4.20 308308608 44.56
HIT HITECH GROUP AUSTRALIA LTD 0.027 0.97 36908500 34.92
NEA NEARMAP LTD 0.075 3.55 1598421504 46.33
GEM G8 EDUCATION LTD 0.10 2.9 1320184448 26.62
SFR SANDFIRE RESOURCES NL 0.17 6.8 1059470400 42.67
BRG BREVILLE GROUP LTD 0.74 18.69 2443190272 23.59
SNL SUPPLY NETWORK LTD 0.26 3.89 158562176 12.96
MVP MEDICAL DEVELOPMENTS INTERNA 0.20 5.3 356411104 28.44
VTG VITA GROUP LTD 0.087 1.59 258572976 16.64
SYR SYRAH RESOURCES LTD 0.035 1.16 392501120 33.16
PME PRO MEDICUS LTD 0.71 18.68 1924158720 24.59
GOR GOLD ROAD RESOURCES LTD 0.032 0.94 829688512 30.63
PNV POLYNOVO LTD 0.034 1.02 664393472 36.59
CCP CREDIT CORP GROUP LTD 1.22 23.06 1255946752 21.39
TPM TPG TELECOM LTD 0.28 6.02 5631815680 23.07
CQE CHARTER HALL EDUCATION TRUST 0.30 3.64 1088269312 13.97
CYL CATALYST METALS LTD 0.082 1.73 136483936 22.07
REA REA GROUP LTD 4.80 80.46 10587227136 17.58
EOL ENERGY ONE LTD 0.10 1.75 39207988 16.5
GLB GLOBE INTERNATIONAL LTD 0.15 1.69 69866536 11.96
DMP DOMINO'S PIZZA ENTERPRISES L 2.98 40.74 3485305344 12.56
OCL OBJECTIVE CORPORATION LTD 0.25 2.85 264745168 10.4
WEB WEBJET LTD 1.34 16.58 2242840576 14.02
LIC LIFESTYLE COMMUNITIES LTD 0.375 5.67 583361856 18.51
SAR SARACEN MINERAL HOLDINGS LTD 0.175 2.92 2395193600 16.62
TNE TECHNOLOGY ONE LTD 0.74 8.43 2676491776 10.95
MWR MGM WIRELESS LTD 0.26 4.03 48263028 14.21
FNP FREEDOM FOODS GROUP LTD 0.37 5.06 1240834560 12.8
INR IONEER LTD 0.012 0.19 280246880 14.08
VOC VOCUS GROUP LTD 0.35 3.86 2401938432 13.2
NAN NANOSONICS LTD 0.32 4.64 1391824896 13.22
EML EML PAYMENTS LTD 0.16 2.06 515522432 12.42
ZEN ZENITH ENERGY LTD/AU 0.045 0.59 57820000 19.33
CIA CHAMPION IRON LTD 0.0195 2.40 1036727424 19.33
AGI AINSWORTH GAME TECHNOLOGY LT 0.08 0.82 277854976 10.96
RRL REGIS RESOURCES LTD 0.045 4.45 2234427648 10.57