Here are the top ASX large cap movers for Wednesday

Pic: John Lamb (The Image Bank) via Getty Images.

Hopes that the new Omicron strain will have a less-pronounced impact on travel and consumer confidence have bolstered stocks this week.

Scientists and vaccine makers are still assessing the severity of Omicron and how well existing vaccines may work against it.

Global oil prices jumped over 3% on optimism that the variant may not be as severe as feared, easing concern over the crude demand outlook. Energy stocks rose 1.8% while the financial sector was up 1.15% and health stocks rose 1.53%.

The materials sector (big miners) led the gains, climbing by 2.23% with tech stocks close on its heels, up 2.16%. BHP (ASX:BHP) Fortescue (ASX:FMG), Rio Tinto (ASX:RIO) and South32 (ASX:S32) were all in the green.

BIG CAP WINNERS

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Code	Name	Price	% Change	Volume	Market Cap
360	Life360 Inc.	11.28	9	3331925	$ 1,826,110,820.91
AKE	Allkem Limited	8.98	6	4595125	$ 5,425,342,736.86
APM	APM Human Services	2.85	15	1491982	$ 2,219,594,816.01
AQZ	Alliance Aviation	4.18	6	131127	$ 636,509,400.12
BTH	Bigtincan Hldgs Ltd	1.07	8	948913	$ 543,277,068.48
CAR	Carsales.Com Ltd.	26.38	5	1467708	$ 7,081,586,415.12
CIA	Champion Iron Ltd	4.93	6	2394612	$ 2,360,252,142.16
CTT	Cettire	3.43	8	733607	$ 1,208,525,157.40
CXL	Calix Limited	6.57	6	251727	$ 995,320,503.59
GRR	Grange Resources.	0.625	5.042	3267021	$ 688,616,525.31
KGN	Kogan.Com Ltd	8.09	6	787584	$ 814,488,152.58
LYC	Lynas Rare Earths	9.36	5.0505	5816033	$ 8,040,486,946.14
MIN	Mineral Resources.	47.07	6	1244422	$ 8,398,168,883.17
MSB	Mesoblast Limited	1.76	10	5367579	$ 1,037,913,712.00
NMT	Neometals Ltd	1.075	6	1339219	$ 556,602,041.94
NTO	Nitro Software Ltd	2.9	5.0725	953432	$ 662,851,734.72
NVX	Novonix Limited	9.1	6	5840938	$ 4,140,398,793.96
PLS	Pilbara Min Ltd	2.49	6	14763553	$ 7,021,176,476.08
PRU	Perseus Mining Ltd	1.555	6	4713557	$ 1,803,865,767.90
RBL	Redbubble Limited	3.33	5	2499709	$ 871,907,904.68
REA	REA Group	168.94	5.1276	277377	$ 21,231,236,771.90
SKO	Serko	6.55	9	58446	$ 713,240,608.42
SZL	Sezzle Inc.	3.59	7	746537	$ 667,799,368.50
UNI	Universal Store	7.59	8	107968	$ 516,030,643.80
Z1P	Zip Co Ltd.	5.29	11	14974128	$ 2,808,742,396.68

APM Human Services (ASX:APM) was top of the leader board, with an intraday gain of 15% on no news.

It was followed by BNPL player Zip Co (ASX:Z1P) up 11%, and Melbourne-based biotech Mesoblast (ASX:MSB).

Up 9% was lifestyle app company Life360 (ASX:360), along with Serko (ASX:SKO).

BIG CAP LOSERS

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Code	Name	Price	% Change	Volume	Market Cap
AFG	Aust Finance Grp	2.58	-2	411213	$ 707,808,946.51
AGG	AngloGold Ashanti	5.6	-3	13090	$ 517,405,037.00
APX	Appen Limited	9.42	-1	1108080	$ 1,172,903,949.48
ASM	Ausstratmaterials	10.17	-2	676768	$ 1,449,467,402.34
DBI	Dalrymple Bay	2.06	-2	186962	$ 1,046,057,117.37
DEG	De Grey Mining	1.095	-2	3744640	$ 1,568,162,230.38
DMP	Domino Pizza Enterpr	124.65	-1	313885	$ 10,913,583,016.26
FLT	Flight Centre Travel	17.99	-1	1883168	$ 3,636,453,931.92
GNE	Genesis Energy Ltd	2.83	-2	2634	$ 3,005,477,714.88
MCY	Mercury NZ Limited	5.65	-4	36277	$ 8,037,575,504.70
NHF	NIB Holdings Limited	6.69	-1	918256	$ 3,112,931,144.05
ORA	Orora Limited	3.38	-2	4977162	$ 3,018,402,608.16
PDL	Pendal Group Ltd	5.69	-1	2344277	$ 2,204,224,629.12
PFP	Propel Funeral	4.3	-1	29080	$ 514,025,470.00
PNV	Polynovo Limited	1.435	-3	2779571	$ 975,547,364.90
PPK	PPK Group Limited	10.2	-3	118594	$ 935,751,790.64
PXA	Pexagroup	16.77	-1	145017	$ 3,009,218,622.36
REG	Regis Healthcare Ltd	1.65	-1	557958	$ 502,392,387.55
SDF	Steadfast Group Ltd	4.79	-4	5942429	$ 4,878,193,785.55
SGP	Stockland	4.31	-2	7203929	$ 10,455,811,879.56
SLC	Superloop Limited	1.255	-1	799429	$ 613,807,032.48
TUA	Tuas Limited	1.95	-3	353561	$ 927,818,042.00
VGL	Vista Group Int Ltd	2.2	-3	10749	$ 522,569,618.70
WHC	Whitehaven Coal	2.49	-2	10173596	$ 2,612,589,906.96
YAL	Yancoal Aust Ltd	2.55	-2	64668	$ 3,419,938,141.83