• Japanese startup OUI is on a mission to halve the world’s blindness with its smartphone-based device
  • Which ASX healthcare companies also have smartphone-based products?
  • A quick look at the best and worst ASX healthcare stocks over the past month

 

The nation that invented QR codes, bullet trains and manga continues to innovate on a global level.

Japan’s latest medical startup, OUI Inc, says it wants to reduce blindness worldwide by 50% by 2025.

Although it might sound a bit ambitious, the company might just have the innovation to back it up.

OUI’s invention revolves around its patented Smart Eye Camera (SEC) product, an ophthalmology medical device that can diagnose eye diseases including trachoma and cataract.

The device can be attached to a smartphone where it’s used to observe the eyelid, cornea, anterior chamber, iris, lens, and anterior vitreous – basically doing all the things a conventional slit-lamp microscope would.

The company says it can be used by anyone, anytime, anywhere to perform eye examinations.

In terms of market size, the number of blindness worldwide is approximately 44 million, and is expected to to triple in 30 years.

More than half of eyesight losses are due to cataracts, which can be restored with early, proper diagnosis, and appropriate treatments.

The device can also evaluate the severity of several other ophthalmic diseases such as dry eye disease, allergic conjunctival disease, and anterior chamber depth.

The Smart Eye Camera is equipped with a high-precision 3D printer. With no need for batteries and minimal moving parts, it is durable and can be carried anywhere.

The disruptive device is currently being used in more than 25 developing countries worldwide, including Kenya, Zambia, Indonesia and Mongolia.

“Of course, we faced many technical hurdles in the course of development, but they weren’t a big deal for us because our desire to provide access to ophthalmologists for as many people as possible was very strong,’’ CEO and co-founder, Eisuke Shimizu told Bloomberg.

 

ASX healthcare stocks focusing on smartphone-based products

On the ASX, a handful of healthcare companies also have diagnostics products that are installed or attached on a smartphone.

 

ResApp Health

In Australia, the now unlisted ResApp is probably the most successful smartphone-based healthcare company, ever.

In October, ResApp’s shares were acquired by global pharma Pfizer in a deal worth $179 million.

ResApp has built an app that can diagnose respiratory diseases like pneumonia, asthma, and even Covid by analysing a patient’s cough.

ResApp’s technology is able to identify the exact disease behind coughing patterns due to the different ways viruses affect the lungs.

In asthma for example, the virus constricts the airway forcing it to get tighter and narrower which causes the wheezing sound.

With pneumonia, you get fluid buildup that causes inflammation in the lungs’ air sacs.

And with Covid, the SARS virus attacks the lungs in a very unique way like a sonar ping, which bounces around causing a distinct coughing sound.

When the Pfizer acquisition was announced, ResApp was in the middle of clinical trials for Covid-19.

 

Medibio (ASX:MEB)

Medibio is a health tech company that’s innovating in the early detection and screening of mental health conditions.

After 25 years of research, Medibio launched its stress tracking mobile app, ‘LUCA’, to identify the true causes of stress in individuals.

The personalised technology was developed by Medibio’s neuroscience team and offers insights into how individual characteristics like personality and emotional intelligence shape responses to stress.

The app also offers tools and cognitive exercise programs to develop solutions tailored to the individual.

Medibio is currently seeking additional business opportunities to satisfy American markets.

The company recently announced the commencement of a clinical trial into the relationship between mental illnesses and sleep disturbances.

 

PainChek (ASX:PCK)

PainChek has a patented algorithmic-based device to measure the level of pain experienced by non-verbal older people and infants.

The cloud-connected app device comes up with a pain score that measures things such as facial expression, behaviour, body movements and, when possible, vocalisation.

The technology has proven itself in the market, especially in the aged care sector.

A global study estimated that up to 80% of residents living in nursing homes experience chronic pain, with half of all residents living with dementia often unable to reliably verbalise their pain.

PainCek’s app, called the PainChek Universal, encapsulates everything into one digital environment, and can be used in both home care, hospitals and aged care residences.

 

Best and worst performing ASX biotechs over the past month

CODE COMPANY PRICE 1 WEEK RETURN % 1 MONTH RETURN % 1 YEAR RETURN % MARKET CAP
KZA Kazia Therapeutics 0.13 -3.70 49.43 -88.84 $22,657,919
VHT Volpara Health Tech 0.82 28.13 45.13 -13.23 $199,169,988
LBT LBT Innovations 0.07 4.41 42.00 -36.89 $23,475,041
TRP Tissue Repair 0.31 29.79 41.86 -37.11 $14,268,008
PAA Pharmaust Limited 0.09 8.54 32.84 -20.89 $28,522,114
PIQ Proteomics Int Lab 1.13 -2.16 32.16 2.73 $133,562,714
AVE Avecho Biotech Ltd 0.01 7.69 27.27 -6.67 $27,568,040
M7T Mach7 Tech Limited 0.74 -0.68 26.72 -5.77 $176,024,695
MDR Medadvisor Limited 0.27 17.39 22.73 -27.03 $141,406,160
RAD Radiopharm 0.14 16.67 21.74 -61.89 $30,852,185
RAD Radiopharm 0.14 16.67 21.74 -61.89 $30,852,185
NEU Neuren Pharmaceut. 8.99 2.74 21.49 140.37 $1,126,133,143
PNV Polynovo Limited 2.49 1.84 21.22 61.89 $1,747,529,660
CYC Cyclopharm Limited 1.56 -1.58 20.00 -18.54 $139,580,739
S66 Star Combo 0.16 3.33 19.23 -51.56 $20,937,862
4DX 4Dmedical Limited 0.46 14.38 18.83 -62.19 $138,411,163
ILA Island Pharma 0.19 -5.00 18.75 -26.92 $8,216,802
CBL Control Bionics 0.16 -11.11 18.52 -61.90 $14,476,644
UBI Universal Biosensors 0.28 7.84 17.02 -71.79 $60,525,289
RSH Respiri Limited 0.05 6.12 15.56 -7.14 $40,186,817
OIL Optiscan Imaging 0.12 15.00 15.00 -30.30 $72,013,644
EXL Elixinol Wellness 0.02 9.52 15.00 -70.51 $7,274,108
NYR Nyrada Inc. 0.16 3.33 14.81 -38.00 $24,181,349
BIT Biotron Limited 0.03 6.90 14.81 -65.58 $27,959,914
ADR Adherium Ltd 0.00 0.00 12.50 -65.38 $24,897,191
PAR Paradigm Bio. 1.45 3.94 11.97 -15.09 $391,347,663
CGS Cogstate Ltd 2.01 5.79 11.67 -15.90 $341,716,196
ATH Alterity Therap Ltd 0.01 11.11 11.11 -52.38 $24,164,184
ALC Alcidion Group Ltd 0.16 0.00 10.71 -42.59 $202,891,048
PXS Pharmaxis Ltd 0.06 10.34 10.34 -39.05 $43,139,682
MDC Medlab Clinical Ltd 8.01 15.58 9.73 -63.17 $17,856,986
ARX Aroa Biosurgery 1.17 -0.85 9.35 20.00 $404,609,265
CTE Cryosite Limited 0.75 -1.32 8.70 63.04 $36,607,172
ANP Antisense Therapeut. 0.09 -7.00 8.14 -48.33 $63,559,178
RHT Resonance Health 0.06 -8.33 7.84 -71.05 $24,886,007
MVP Medical Developments 1.66 6.77 7.82 -63.60 $146,718,798
MEM Memphasys Ltd 0.02 0.00 7.14 -81.06 $15,352,326
IHL Incannex Healthcare 0.20 9.46 6.58 -67.07 $309,467,020
SOM SomnoMed Limited 1.32 1.94 6.48 -36.78 $108,828,499
AT1 Atomo Diagnostics 0.06 9.43 6.42 -77.25 $33,111,677
GSS Genetic Signatures 0.94 2.17 6.21 -43.03 $135,518,666
CPH Creso Pharma Ltd 0.02 -4.55 5.00 -76.92 $39,176,950
DOC Doctor Care Anywhere 0.07 30.77 4.62 -87.41 $22,365,177
EPN Epsilon Healthcare 0.03 8.70 4.17 -63.24 $7,358,673
AN1 Anagenics Limited 0.03 -12.90 3.85 -50.91 $5,974,193
MX1 Micro-X Limited 0.14 3.85 3.85 -47.06 $69,376,275
ATX Amplia Therapeutics 0.09 3.53 3.53 -48.24 $16,684,476
MVF Monash IVF Group Ltd 1.03 9.57 3.52 3.52 $407,168,408
BOT Botanix Pharma Ltd 0.06 1.69 3.45 -17.81 $67,686,421
PAB Patrys Limited 0.03 0.00 3.33 -18.42 $63,766,992
TRU Truscreen 0.04 0.00 2.63 -50.00 $14,151,784
CMP Compumedics Limited 0.20 5.26 2.56 -50.00 $35,432,590
IMC Immuron Limited 0.08 5.26 2.56 -33.33 $17,540,473
OCC Orthocell Limited 0.42 3.70 2.44 -10.64 $81,839,274
SDI SDI Limited 0.91 2.82 2.25 -5.70 $108,167,632
VLS Vita Life Sciences.. 1.45 4.32 1.75 -30.29 $76,779,837
CAJ Capitol Health 0.32 0.00 1.59 -16.88 $340,327,212
AGH Althea Group 0.06 0.00 1.59 -70.91 $23,128,254
CDX Cardiex Limited 0.38 -2.60 1.35 -27.88 $49,393,975
EYE Nova EYE Medical Ltd 0.25 -18.03 0.00 -24.24 $37,929,697
RNO Rhinomed Ltd 0.11 0.00 0.00 -61.81 $31,429,166
BDX Bcaldiagnostics 0.06 0.00 0.00 -48.94 $8,165,683
SCU Stemcell United Ltd 0.01 0.00 0.00 0.00 $14,995,837
HGV Hygrovest Limited 0.07 0.00 0.00 25.00 $16,096,779
IRX Inhalerx Limited 0.06 0.00 0.00 -33.33 $10,299,683
IVX Invion Ltd 0.01 0.00 0.00 -57.14 $57,780,829
ICS ICSGlobal Limited 0.58 0.00 0.00 0.00 $6,054,605
AC8 Auscann Grp Hlgs Ltd 0.04 0.00 0.00 -51.81 $17,621,884
HCT Holista CollTech Ltd 0.03 -3.45 0.00 -34.88 $7,806,402
OPT Opthea Limited 0.90 -0.56 0.00 -29.53 $410,888,245
NC6 Nanollose Limited 0.06 -3.23 0.00 -36.84 $8,337,637
NXS Next Science Limited 0.70 5.30 0.00 -41.60 $152,500,995
PTX Prescient Ltd 0.13 0.00 0.00 -47.92 $90,194,529
OVN Oventus Medical Ltd 0.02 0.00 0.00 -76.47 $4,834,531
1ST 1St Group Ltd 0.01 0.00 0.00 -28.92 $11,593,564
CYP Cynata Therapeutics 0.31 3.33 0.00 -43.64 $43,699,361
DVL Dorsavi Ltd 0.01 9.09 0.00 -39.06 $5,682,075
BPH BPH Energy Ltd 0.02 0.00 0.00 -50.43 $15,796,781
TLX Telix Pharmaceutical 6.96 9.26 -1.69 -19.07 $2,236,543,384
BXN Bioxyne Ltd 0.03 2.00 -1.92 2.00 $17,306,780
NTI Neurotech Intl 0.07 2.14 -2.05 23.28 $55,229,381
IIQ Inoviq Ltd 0.64 -5.22 -2.31 -46.86 $57,971,782
CHM Chimeric Therapeutic 0.08 3.80 -2.38 -65.97 $26,715,047
IDT IDT Australia Ltd 0.08 3.85 -2.41 -64.78 $19,281,744
ZLD Zelira Therapeutics 1.04 2.97 -2.80 -80.83 $10,199,629
RCE Recce Pharmaceutical 0.65 -5.80 -2.99 -51.49 $114,925,655
PSQ Pacific Smiles Grp 1.51 4.14 -3.21 -44.69 $240,968,726
PBP Probiotec Limited 2.17 -2.25 -3.56 -8.05 $176,471,791
VBS Vectus Biosystems 0.79 -0.63 -3.66 -39.69 $42,019,720
LCT Living Cell Tech. 0.01 -3.85 -3.85 108.33 $15,424,365
AHC Austco Healthcare 0.12 -7.69 -4.00 -14.29 $34,778,081
ZNO Zoono Group Ltd 0.10 3.23 -4.00 -77.67 $16,525,597
ALA Arovella Therapeutic 0.02 4.35 -4.00 -33.33 $16,164,831
ACW Actinogen Medical 0.10 3.26 -4.04 -32.14 $171,593,954
SHG Singular Health 0.11 4.76 -4.35 -66.15 $7,748,051
IMM Immutep Ltd 0.30 0.00 -4.76 -34.07 $268,185,166
CAN Cann Group Ltd 0.20 -4.88 -4.88 -31.58 $79,270,397
HXL Hexima 0.02 0.00 -5.00 -95.10 $3,173,753
ACR Acrux Limited 0.07 0.00 -5.56 -32.00 $19,474,721
NOX Noxopharm Limited 0.14 7.69 -6.67 -67.44 $39,452,123
EZZ EZZ Life Science 0.38 -2.56 -7.32 -24.00 $4,912,600
RHY Rhythm Biosciences 0.95 -8.70 -7.35 -37.83 $211,738,399
IMU Imugene Limited 0.16 -4.55 -7.35 -58.55 $995,365,934
RAC Race Oncology Ltd 2.00 4.71 -7.41 -37.89 $333,669,150
AHK Ark Mines Limited 0.21 3.75 -7.78 -5.68 $7,181,596
PYC PYC Therapeutics 0.06 -4.84 -7.81 -52.80 $194,036,492
ONE Oneview Healthcare 0.11 13.40 -8.33 -60.71 $58,620,617
ICR Intelicare Holdings 0.02 -12.00 -8.33 -71.17 $4,596,139
DXB Dimerix Ltd 0.16 3.33 -8.82 -42.59 $48,131,050
PCK Painchek Ltd 0.03 -11.43 -8.82 -48.17 $41,484,972
GLH Global Health Ltd 0.20 5.26 -9.09 -48.05 $11,600,676
1AD Adalta Limited 0.04 2.56 -9.09 -50.00 $12,567,390
ADO Anteotech Ltd 0.05 2.88 -9.32 -82.74 $103,399,204
VTI Vision Tech Inc 0.38 -6.25 -10.71 -58.56 $11,748,414
CU6 Clarity Pharma 0.85 -5.56 -11.46 0.00 $154,616,711
PGC Paragon Care Limited 0.30 1.69 -11.76 -24.05 $197,353,779
MXC Mgc Pharmaceuticals 0.01 -4.55 -12.50 -74.39 $31,524,321
OSL Oncosil Medical 0.04 -6.52 -14.00 3.63 $44,740,902
RGS Regeneus Ltd 0.04 -4.65 -14.58 -52.33 $12,563,913
IBX Imagion Biosys Ltd 0.02 4.55 -14.81 -68.92 $24,669,008
IPD Impedimed Limited 0.07 -8.00 -19.77 -61.67 $124,996,544
JTL Jayex Technology Ltd 0.01 -23.08 -23.08 -52.38 $2,492,285
LDX Lumos Diagnostics 0.04 -19.57 -24.49 -96.33 $8,658,797
MEB Medibio Limited 0.00 -25.00 -25.00 -70.00 $4,980,891
AMT Allegra Orthopaedics 0.08 -22.00 -25.71 -51.25 $8,147,818
NSB Neuroscientific 0.11 11.70 -30.00 -69.57 $14,347,164
OSX Osteopore Limited 0.13 -3.70 -35.00 -53.57 $16,111,538
BNO Bionomics Limited 0.03 -6.06 -45.61 -71.82 $44,062,063
BWX BWX Limited 0.24 17.50 -62.70 -93.50 $49,996,876
TSN The Sust Nutri Grp 0.02 -8.33 -84.29 -88.72 $2,412,128
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Volpara Health Tech (ASX:VHT)

Volpara was one of the best performers for the month, up 45%, after recording five new contracts with a combined value of NZ$12.3m.

The company signed five 5-year contacts with some of the US’s leading healthcare providers: Bon Secours Mercy Health, Northside Hospital, Adventist Health, Duly Health and Care, and Onsite Women’s Health.

A 5-year renewal contract secured with Centura Health represents a further US$887K in TCV (total contract value).

PharmAust (ASX:PAA)

PharmAust’s Phase 1/2 Motor Neurone Disease (MND) clinical trial has successfully completed its first patient cohort.

PharmAust’s Monepantel (MPL) was well tolerated by all MND patients at the first dosing level, with all of six patients in cohort 1 electing to continue on MPL treatment.

Patient recruitment at the next dosing level expected to begin later this month.

Safety and efficacy data from the trial will also be used to facilitate a Phase 2 study in COVID-19 patients.

Proteomics (ASX:PIQ)

PIQ gained US approval for its PromarkerD test for diabetic kidney disease.

The CPT PLA (Proprietary Laboratory Analyses) code has been issued by the American Medical Association, and was a key approval in getting reimbursement coverage of the PromarkerD test by both Medicare and private health insurers in America.

The approval is significant in the commercialisation of the test in the US market.

PIQ has also signed a letter of intent with Sonic Healthcare (ASX:SHL) to use the test in their US labs, which has been extended until the end of January.

Mach7 Tech (ASX:M7T)

M7T signed up Nasdaq-listed Akumin Inc, an outpatient radiology service provider in the US, as a new customer to deploy its entire cloud-based enterprise imaging platform.

The total contract value is ~$16.7 million, which will be staged annually across the life of the contract with $7.5m of that expected to be recognised in FY23.

Annual support fees will be weighted to the second half of the contract term.