• Artificial intelligence is set to disrupt the healthcare sector
  • AI could also help in drugs discovery
  • Telix delivers first quarterly revenue of $100 million

 

Moody’s Analytics’ chief economist, Mark Zandi, said the healthcare industry’s current top challenges are a severe shortage of labor and soaring labor costs.

Speaking at the recent HIMSS 2023 Global Health Conference and Exhibition, Zandi also believes that healthcare prices have “barely kept pace with overall inflation.”

“This combination of factors is going to be very challenging for the healthcare sector for the foreseeable future,” Zandi said, adding that an aging workforce is also a top contributor to the problem.

But he believes there is a way out of this situation, and that involves rising productivity in the sector through technology to get more value while spending less money.

“What can increase healthcare productivity? Artificial intelligence (AI) and machine learning,” Zandi said.

Zandi explained that AI and machine learning have been around for a long time, but only now do we have a lot more and better data to work with.

“AI is the way out of the box… and we need to get out of the box,” Zandi told attendees.

“Because at the end of the day, the nation’s economy-wide fiscal health relies on the healthcare sector. There is enormous opportunity here in helping to make productivity gains going forward.”

 

AI to help in drug discovery

Goldman agrees with that assessment and in its recently circulated Byte-ology report, the bank said the healthcare sector is ripe for disruption.

From a data standpoint, the healthcare industry produces and relies upon massive amounts of data from diverse sources, so that creates a rich environment for applying AI and machine learning.

”The need for these technologies is there given the inefficiencies in the healthcare system,” said Goldman.

It is estimated that it takes more than eight years and US$2 billion to develop a drug, and the likelihood of failure is quite high.

“AI, including generative AI, is among the technologies that have the potential to create safer, more efficacious drugs and to streamline personalised care,” said the GS report.

But according to Goldman, despite all previous innovation, we’re still just scratching the surface.

AI’s role only came into the spotlight during the Covid-19 pandemic response, when it helped companies develop Covid-19 mRNA vaccines and therapeutics at unprecedented speeds.

As for its future use in drug discovery, Goldman said AI can be utilised to identify novel targets, design drugs, as well as predict drug interactions to minimise the need for the costly traditional methodology of wet lab trial and error development.

“Uptake would greatly benefit from regulatory support, standardised benchmarks to evaluate performance, and public forums to improve collaboration and transparency,” said Goldman.

 

To the ASX….

Best and worst performing ASX biotechs over the past month

CODE COMPANY PRICE 1 MONTH RETURN % 6 MONTH RETURN % 1 WEEK RETURN % 1 YEAR RETURN % MARKET CAP
4DX 4Dmedical Limited 0.85 156.06 32.03 4.32 14.97 $252,106,031
ALA Arovella Therapeutic 0.08 142.42 185.71 17.65 95.12 $59,767,258
ONE Oneview Healthcare 0.09 51.61 -30.37 23.68 -63.14 $43,744,308
IPD Impedimed Limited 0.19 48.00 115.12 54.17 54.17 $321,681,372
AHK Ark Mines Limited 0.31 47.62 5.08 -4.62 -28.74 $10,729,132
IDT IDT Australia Ltd 0.09 46.55 -15.00 11.84 -45.16 $20,691,193
TLX Telix Pharmaceutical 10.28 46.23 47.91 5.01 137.41 $3,342,450,617
MEM Memphasys Ltd 0.02 42.86 33.33 5.26 -66.73 $19,190,408
CDX Cardiex Limited 0.35 38.00 18.97 11.29 7.81 $53,082,243
CYC Cyclopharm Limited 2.06 37.79 50.37 -3.29 37.33 $192,282,468
ADR Adherium Ltd 0.00 33.33 0.00 33.33 -60.00 $19,985,753
KZA Kazia Therapeutics 0.19 32.14 15.63 -9.76 -80.63 $45,605,823
PXS Pharmaxis Ltd 0.06 29.79 -3.17 10.91 -39.00 $41,016,305
AMT Allegra Orthopaedics 0.07 27.27 -30.00 0.00 -63.16 $7,312,144
BDX Bcaldiagnostics 0.09 26.47 30.30 17.81 -18.10 $11,704,145
JTL Jayex Technology Ltd 0.01 25.00 100.00 0.00 -23.08 $2,531,507
VTI Vision Tech Inc 0.25 22.50 -7.55 -12.50 -51.96 $8,722,235
ATX Amplia Therapeutics 0.11 22.09 0.00 10.53 -19.23 $19,400,554
BPH BPH Energy Ltd 0.03 19.05 47.06 25.00 -31.16 $19,307,176
PSQ Pacific Smiles Grp 1.40 18.64 -0.36 16.67 -38.86 $217,031,436
PGC Paragon Care Limited 0.27 17.39 -22.86 3.85 -26.03 $181,320,130
M7T Mach7 Tech Limited 0.68 17.24 9.68 13.33 -2.16 $146,210,522
VBS Vectus Biosystems 0.55 17.02 -36.05 10.00 -57.85 $29,254,235
CHM Chimeric Therapeutic 0.07 16.39 -17.44 7.58 -43.20 $31,470,795
EZZ EZZ Life Science 0.48 15.66 52.38 18.52 29.73 $25,195,950
PAA Pharmaust Limited 0.10 15.48 24.36 -3.00 7.78 $31,374,326
ATH Alterity Therap Ltd 0.01 14.29 -38.46 0.00 -57.89 $19,519,181
AGH Althea Group 0.06 14.00 -32.14 0.00 -67.43 $21,320,525
IMC Immuron Limited 0.08 13.04 0.00 -4.88 -37.60 $18,223,868
CGS Cogstate Ltd 1.61 11.81 -13.44 12.59 -26.48 $268,325,018
MVF Monash IVF Group Ltd 1.15 11.65 21.05 5.02 -8.00 $455,872,763
RAD Radiopharm 0.20 11.43 69.57 8.33 -10.35 $51,373,742
RAD Radiopharm 0.20 11.43 69.57 8.33 -10.35 $51,373,742
CMP Compumedics Limited 0.16 10.71 -31.11 10.71 -42.59 $24,802,813
ILA Island Pharma 0.08 9.72 -54.86 1.28 -58.42 $6,542,112
RCE Recce Pharmaceutical 0.64 9.48 -9.93 0.79 -29.05 $113,191,487
RGS Regeneus Ltd 0.01 9.09 -70.73 -20.00 -78.57 $3,983,680
BXN Bioxyne Ltd 0.03 8.70 -7.41 0.00 47.06 $16,641,135
AHC Austco Healthcare 0.14 8.00 12.50 3.85 8.00 $39,256,673
IIQ Inoviq Ltd 0.55 7.84 0.00 17.02 -12.70 $50,610,286
BIT Biotron Limited 0.03 7.41 -14.45 1.75 -58.98 $26,156,402
NEU Neuren Pharmaceut. 14.07 7.00 94.07 3.08 264.51 $1,809,889,167
CAN Cann Group Ltd 0.16 6.90 -32.61 3.33 -58.67 $60,162,454
RAC Race Oncology Ltd 1.88 6.84 -19.18 -1.57 -17.76 $306,491,666
TRP Tissue Repair 0.22 6.17 -20.37 2.38 -35.82 $9,589,973
OIL Optiscan Imaging 0.09 5.75 -40.65 -7.07 -34.29 $56,358,504
OCC Orthocell Limited 0.39 5.48 -4.94 -9.41 -2.53 $77,934,713
VLS Vita Life Sciences.. 1.47 5.00 -3.61 2.08 -28.47 $79,056,030
RHT Resonance Health 0.04 4.76 -34.33 -8.33 -63.33 $20,277,487
S66 Star Combo 0.11 4.76 -37.14 0.00 -45.00 $14,859,128
NC6 Nanollose Limited 0.05 4.55 -23.33 -8.00 -51.06 $6,848,773
UBI Universal Biosensors 0.26 4.00 -5.45 -10.34 -62.86 $59,463,442
CAJ Capitol Health 0.27 3.85 -18.18 -3.57 -16.92 $287,151,085
IMM Immutep Ltd 0.27 3.85 -6.90 5.88 -14.29 $228,616,863
ZLD Zelira Therapeutics 0.94 2.17 -20.34 -3.09 -54.15 $10,666,326
NTI Neurotech Intl 0.05 2.04 -61.54 -15.25 2.04 $45,443,293
RHY Rhythm Biosciences 0.51 2.02 -58.61 5.21 -64.44 $96,639,577
NXS Next Science Limited 0.66 1.54 -10.81 -8.33 -21.89 $150,353,094
ARX Aroa Biosurgery 1.05 0.72 23.24 1.70 12.63 $361,980,489
VHT Volpara Health Tech 0.77 0.65 13.24 -0.65 -9.41 $188,026,533
ALT Analytica Limited 0.00 0.00 0.00 0.00 -33.33 $4,613,801
TSN The Sust Nutri Grp 0.02 0.00 -87.86 -5.56 -90.00 $2,252,206
PBP Probiotec Limited 2.40 0.00 10.60 0.84 5.73 $191,923,238
MEB Medibio Limited 0.00 0.00 -33.33 -33.33 -75.00 $4,150,594
ICS ICSGlobal Limited 0.58 0.00 0.00 0.00 0.00 $6,054,605
AC8 Auscann Grp Hlgs Ltd 0.04 0.00 0.00 0.00 -38.46 $17,621,884
PIQ Proteomics Int Lab 0.89 0.00 -2.75 -2.75 -11.06 $106,867,283
BWX BWX Limited 0.20 0.00 -68.25 0.00 -89.24 $39,997,500
BNO Bionomics Limited 0.02 0.00 -62.71 15.79 -63.93 $32,312,179
TD1 Tali Digital Limited 0.00 0.00 -20.00 0.00 -78.18 $6,590,311
OVN Oventus Medical Ltd 0.02 0.00 0.00 0.00 -47.37 $4,834,531
CPH Creso Pharma Ltd 0.01 0.00 -67.74 0.00 -82.46 $19,228,569
MDC Medlab Clinical Ltd 6.60 0.00 -37.08 0.00 -60.00 $15,071,113
GTG Genetic Technologies 0.00 0.00 0.00 -25.00 -25.00 $34,624,974
OSL Oncosil Medical 0.01 0.00 -70.16 20.00 -75.49 $11,930,907
IMU Imugene Limited 0.13 0.00 -34.21 -10.71 -39.02 $802,879,889
IHL Incannex Healthcare 0.12 0.00 -54.72 0.00 -69.62 $190,441,243
CU6 Clarity Pharma 0.74 -1.33 13.85 -1.33 48.00 $136,748,321
SDI SDI Limited 0.83 -2.35 1.22 0.00 -1.19 $95,686,752
CTE Cryosite Limited 0.76 -2.56 14.29 4.11 32.17 $36,607,172
DOC Doctor Care Anywhere 0.05 -3.70 -23.53 -9.57 -80.38 $18,698,755
PTX Prescient Ltd 0.10 -4.00 -40.00 0.00 -23.20 $74,726,866
GSS Genetic Signatures 0.75 -4.49 1.36 -7.45 -42.69 $109,705,587
EXL Elixinol Wellness 0.02 -4.76 -28.57 0.00 -62.96 $7,504,184
OSX Osteopore Limited 0.08 -4.76 -61.48 -15.79 -59.55 $11,538,281
OPT Opthea Limited 0.73 -5.23 -26.77 6.62 -26.02 $343,362,184
IBX Imagion Biosys Ltd 0.02 -5.88 -46.67 0.00 -71.43 $17,514,987
HCT Holista CollTech Ltd 0.01 -6.67 -57.58 -12.50 -60.00 $3,345,601
NSB Neuroscientific 0.07 -6.67 -22.22 -6.67 -74.07 $10,473,430
LBT LBT Innovations 0.04 -6.98 -35.48 0.00 -49.37 $12,944,107
HGV Hygrovest Limited 0.06 -7.58 -14.08 22.00 -1.61 $13,107,377
SOM SomnoMed Limited 0.91 -7.61 -41.48 -4.21 -53.09 $75,310,977
RNO Rhinomed Ltd 0.08 -7.95 -37.69 -10.00 -61.43 $23,429,015
ANP Antisense Therapeut. 0.08 -8.05 -4.76 2.56 -27.27 $52,206,534
GLH Global Health Ltd 0.16 -8.82 -38.00 -22.50 -45.61 $8,990,524
MDR Medadvisor Limited 0.23 -9.00 26.39 -3.19 -10.78 $119,728,166
PNV Polynovo Limited 1.64 -9.39 -17.17 -0.30 68.21 $1,149,237,530
IRX Inhalerx Limited 0.05 -10.00 -35.71 0.00 -57.14 $8,539,513
ICR Intelicare Holdings 0.02 -10.00 -35.33 -5.26 -78.90 $3,760,477
PCK Painchek Ltd 0.03 -10.00 -6.90 -3.57 -32.28 $35,045,718
MVP Medical Developments 1.03 -10.82 -38.32 3.00 -70.10 $86,305,175
MX1 Micro-X Limited 0.10 -10.91 -27.41 4.26 -51.00 $50,402,800
LCT Living Cell Tech. 0.01 -11.11 -37.70 -11.11 34.99 $11,787,186
ACR Acrux Limited 0.06 -12.50 -31.71 7.69 -30.00 $15,815,551
IVX Invion Ltd 0.01 -12.50 -36.36 0.00 -51.72 $44,940,645
PYC PYC Therapeutics 0.06 -13.04 -14.29 -9.09 -34.07 $194,432,168
ACW Actinogen Medical 0.06 -13.24 -54.62 -10.61 -37.23 $105,342,625
ADO Anteotech Ltd 0.03 -14.10 -41.23 -4.29 -72.08 $69,697,910
EPN Epsilon Healthcare 0.02 -14.29 -37.93 0.00 -53.85 $5,406,372
DVL Dorsavi Ltd 0.01 -14.29 -7.69 -7.69 -41.96 $6,500,257
CBL Control Bionics 0.14 -15.15 -22.22 -6.67 -61.11 $12,667,064
RSH Respiri Limited 0.05 -16.13 26.83 0.00 1.96 $41,318,581
DXB Dimerix Ltd 0.10 -16.52 -41.82 -3.03 -33.79 $29,841,251
MXC Mgc Pharmaceuticals 0.01 -16.67 -53.13 7.14 -65.91 $25,588,151
AT1 Atomo Diagnostics 0.04 -16.67 -41.67 0.00 -70.83 $20,266,630
BOT Botanix Pharma Ltd 0.09 -18.10 36.51 -7.53 8.18 $105,755,054
NYR Nyrada Inc. 0.09 -18.18 -41.94 -10.00 -52.63 $14,664,818
SHG Singular Health 0.06 -18.42 -50.40 6.90 -67.37 $7,268,798
AN1 Anagenics Limited 0.02 -19.23 -39.43 -19.23 -50.70 $9,506,119
1AD Adalta Limited 0.03 -19.35 -50.98 -3.85 -63.24 $8,199,774
EYE Nova EYE Medical Ltd 0.24 -20.34 6.82 -11.32 -9.62 $40,887,558
1ST 1St Group Ltd 0.01 -22.22 -22.22 -22.22 -30.00 $8,121,200
ALC Alcidion Group Ltd 0.10 -25.38 -30.71 -15.65 -47.57 $125,538,836
PAR Paradigm Bio. 1.01 -25.46 -24.63 -4.27 -17.29 $282,344,007
HXL Hexima 0.01 -26.67 -47.62 0.00 -96.33 $1,837,436
ZNO Zoono Group Ltd 0.05 -26.76 -65.33 -5.45 -75.81 $8,745,520
TRU Truscreen 0.02 -27.59 -48.78 -16.00 -65.57 $8,749,482
PAB Patrys Limited 0.02 -31.82 -21.05 -6.25 -34.78 $30,859,026
AVE Avecho Biotech Ltd 0.01 -33.33 -33.33 20.00 -64.71 $9,189,347
NOX Noxopharm Limited 0.06 -37.37 -66.94 -9.85 -81.69 $17,534,277
CYP Cynata Therapeutics 0.18 -37.50 -47.76 -12.50 -53.95 $28,234,925
LDX Lumos Diagnostics 0.02 -40.00 -64.00 -10.00 -94.09 $4,648,141
SCU Stemcell United Ltd 0.01 -62.03 -62.03 0.00 -62.03 $6,423,649
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4D Medical (ASX:4DX)

4DX rose over 160% in the past month after announcing the first contract win in the US, with the University of Miami.

It was a milestone in the company’s commercialisation journey of its X-ray Velocimetry Lung Ventilation Analysis Software.

Furthermore, this milestone was completed with its clinical trial partners at the University of Miami, who have developed such an extensive understanding of the XV Technology.

The Australian Lung Foundation states that around 1 in 7 Australians over 40 have COPD, and around half of these don’t know that they have the condition. However, if diagnosed early enough (prior to the occurrence of structural changes in the lungs), COPD is a treatable condition.

 

Arovella Therapeutics (ASX:ALA)

ALA’s share price more than doubled during the month after saying that lead drug ALA-101 confers significant anti-tumour effect and survival benefit in aggressive leukemia model.

The company presented new data at the American Association for Cancer Research (AACR) Annual Meeting for CAR19-iNKT cells.

ALA says clinical data indicated that ALA-101 has the potential to be a novel ‘off-the-shelf’ cell therapy to treat CD19-expressing leukemias and lymphomas.

 

IDT Australia (ASX:IDT)

IDT has delivered another set of improved sales results in Q3 as it executes on its turnaround strategy.

Sales in the latest quarter jumped 26% to $2.1m vs Q2.

The company’s Specialty Orals Division is driving most of the increase due to growth in medicinal cannabis and the opening of the psychedelics market.

 

Telix Pharma (ASX:TLX)

Australia’s second largest biotech after CSL reported March quarter revenues of $100.1 million, driven by global sales of its prostate cancer imaging agent called Illuccix.

Demand for Illuccix in the US continues to increase on the back of strong clinical results with sales of $97.5 million (up from $76.8 million in the prior quarter).

Telix CEO Dr Christian Behrenbruch said: “In one year since the commercial launch of Illuccix and five years since listing on the ASX, Telix has delivered a significant milestone with its first $100 million revenue quarter.

“We are making a meaningful difference in the lives of thousands of prostate cancer patients and delivering on our mission of global leadership in radiopharmaceuticals.

“Telix is able to fund the development of new imaging agents and novel therapeutics, evident in recent achievements and delivery of our second consecutive quarter of positive operating cash flow,” Behrenbruch added.