• Expert says Australia is not capitalising on its biotech research
  • Morningstar says biotech still best sector to hold during a recession
  • We look at ASX biotech winners in September

 

The MD of one of Australia’s global biotech funds says Australia’s unsophisticated approach to capitalising on research will leave it unable to capitalise on an upturn in biotech markets.

Returning from one of his regular trips to the US, Charles Williams, the managing director of specialist life sciences fund, HB Biotechnology, remains convinced that the Australian biotech ecosystem is less sophisticated than the US and Europe – and is likely to remain this way.

He also thinks a biotech boom appears to be on the horizon, but Australia may not be fully geared up to capitalise on this potential growth.

While Australia does not lack talent and is home to some of the most productive biomedical research facilities in the world, one significant hurdle is the comparatively limited funding and lack of depth in quality management available for biotech startups and research initiatives in Australia.

This means that our best biotech companies are usually being sold to Big Pharma of the world at a very early stage of their development.

Williams believes that despite having one of the world’s top five biotechnology research centres on Australian lands, the country still fails to compete with the US and Europe when it comes to commercialisation.

He advised investors, however, that biotech offers a more desirable investment opportunity with better returns as we approach choppy waters with recession potentially being around the corner.

“Investment in biotech in Australia still needs to improve per global comparison,” he said.

“But there is great benefit in looking at biotech as a significant investment sector rather than simply as an area of research.”

 

Biotech still best sector in a recession – Morningstar

Meanwhile, the S&P/ASX 200 Health Care [XHJ] index was down -5.5% in September.

In the US, the benchmark NASDAQ Biotechnology Index was also down -4.81% as traders weighed the prospects of a “higher for longer” strategy by the US Fed Reserve.

According to Morningstar analyst, Amy Arnott, healthcare and consumer staples will always be one of the most resilient performers during periods of economic weakness.

“Consumers can’t easily cut back on prescription drugs, medical devices, or household basics like canned goods and paper towels even if they’re feeling the effects of a weaker economy,” she said.

But does the prospect of a looming recession mean you should overhaul your portfolio?

“No. In fact, making wholesale shifts in portfolio holdings is usually a bad idea,” Arnott said, adding that being mentally prepared for a recession can actually help investors survive a tough period ahead.

“Studying how the market has historically performed can help you set expectations for how your holdings might react if and when the economy weakens,” she said.

 

ASX Biotech Winners in September

Code Name Price % Month Change Market Cap
BIT Biotron Limited 0.068 134.48 $61,332,253
VTI Vision Tech Inc 0.335 52.27 $10,625,268
EPN Epsilon Healthcare 0.032 45.45 $9,611,328
NTI Neurotech Intl 0.067 39.58 $59,114,735
ALA Arovella Therapeutic 0.068 38.78 $61,333,607
PCK Painchek Ltd 0.041 32.26 $57,659,231
RHT Resonance Health 0.079 31.67 $36,407,306
DOC Doctor Care Anywhere 0.060 30.43 $21,998,535
RAD Radiopharm 0.120 29.03 $28,717,564
PIQ Proteomics Int Lab 1.110 26.14 $135,791,540
EZZ EZZ Life Science 0.680 25.93 $29,039,400
GTG Genetic Technologies 0.003 25.00 $28,854,145
AN1 Anagenics Limited 0.023 21.05 $8,409,259
ICR Intelicare Holdings 0.015 15.38 $3,133,731
RGS Regeneus Ltd 0.008 14.29 $2,451,495
GLH Global Health Ltd 0.170 13.33 $9,868,421
GSS Genetic Signatures 0.510 13.33 $73,137,058
UBI Universal Biosensors 0.270 12.50 $57,339,747
AHC Austco Healthcare 0.190 11.76 $55,250,132
1ST 1St Group Ltd 0.010 11.11 $14,169,912
JTL Jayex Technology Ltd 0.010 11.11 $2,812,785
RAC Race Oncology Ltd 0.905 11.04 $147,577,246
VLS Vita Life Sciences.. 1.680 10.89 $90,601,748
MDR Medadvisor Limited 0.230 9.52 $125,720,973
M7T Mach7 Tech Limited 0.795 8.16 $191,304,333
ILA Island Pharma 0.085 7.59 $6,907,820
1AI Algorae Pharma 0.015 7.14 $22,900,363
KZA Kazia Therapeutics 0.165 6.45 $38,997,647
ONE Oneview Healthcare 0.250 6.38 $166,279,825
CU6 Clarity Pharma 1.170 6.36 $306,375,303
RSH Respiri Limited 0.034 6.25 $34,000,005
TLX Telix Pharmaceutical 11.400 6.05 $3,695,724,625
CGS Cogstate Ltd 1.525 5.90 $264,108,874
BPH BPH Energy Ltd 0.018 5.88 $18,374,175
MVF Monash IVF Group Ltd 1.260 5.88 $490,939,898
CMP Compumedics Limited 0.185 5.71 $32,775,145
CYC Cyclopharm Limited 2.830 5.60 $265,726,603
NOX Noxopharm Limited 0.039 5.41 $11,397,280
BDX Bcaldiagnostics 0.105 5.00 $25,524,208
1AD Adalta Limited 0.022 4.76 $9,741,690
MX1 Micro-X Limited 0.125 4.17 $64,553,124
CYP Cynata Therapeutics 0.130 4.00 $23,352,132
PSQ Pacific Smiles Grp 1.405 2.18 $224,212,623
IMM Immutep Ltd 0.280 1.82 $332,445,739
AMT Allegra Orthopaedics 0.061 1.67 $7,296,273
ANP Antisense Therapeut. 0.068 1.49 $61,305,058
PBP Probiotec Limited 2.640 0.76 $214,693,792
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Biotron (ASX:BIT) 

Biotron shares spiked in the last week of September, and the company was promptly issued a speeding ticket by the ASX.

This follows a Tuesday message to shareholders from CEO Michelle Miller, who talked about the near-term outlook for BIT as it nears the final stage of three Phase 2 clinical trials for HIV‐1 and COVID‐19.

Biotron is developing a batch of new anti-viral therapies which potentially have broad applications.

 

Neurotech (ASX:NTI)

Neurotech announced the completion of patient recruitment in the company’s Phase 1/2 clinical trial investigating the use of NTI164 in female Rett Syndrome patients.

The NTIRTT1 clinical trial will examine the effects of daily oral treatment of NTI164 in 14 Rett Syndrome patients, following on from the company’s successful presentation at the 2023 International Rett Syndrome Scientific Meeting in Tennessee.

As a result of the rapid recruitment into this study, Neurotech anticipates results of the trial in early Q1 2024, which will provides Neurotech an accelerated clinical result in this rare neurological disorder where safe and effective therapies are of paramount importance.

 

Arovella Therapeutics (ASX:ALA)

ALA announced that David Simmonds, non-executive director, will retire from the board of directors at the 2023 Annual General Meeting, expected to be held on 10 November.

Simmonds was appointed to the board in March 2019.

ALA has upcoming milestones, including a still-in-progress due diligence to obtain a licence for a technology owned by the University of North Carolina.

ALA is also in preliminary early stage negotiations to enter into an intellectual property licence agreement with a prospective licensor, Sparx Therapeutics.

The company’s lead asset is ALA-101, a potential treatment for B cell lymphomas and leukaemias.

 

Proteomics (ASX:PIQ)

PIQ surged after announcing a major milestone in the commercialisation of its predictive test for diabetic kidney disease, PromarkerD, with the US Centers for Medicare & Medicaid Services (CMS) setting a national reimbursement price for the test in the US.

The CMS has listed and assigned a reimbursement payment rate of US$390.75 for PromarkerD in the US.

This rate is set for all patients accessing government-funded healthcare in the US – Medicare covers those over the age of 65, while Medicaid covers eligible low-income Americans.

It will be delivered through Sonic Healthcare USA, and is expected to become final after a 30-day period of public comment, with effective date of 1 January 2024.

 

Genetic Technologies (ASX:GTG)

GTG says that its expanded geneType Multi-Risk Test is now available to order in Australia.

The three new diseases – pancreatic cancer, melanoma, and atrial fibrillation – were approved for sale in Australia by the National Association of Testing Authority (NATA).

Separately, GTG announced that a Medical Research Future Fund (MRFF) grant has been awarded to a group of renowned national and international research and charity organisations.

The grant will provide funding for the CASSOWARY Trial – a trial aimed to investigate how funding for genomics-based cancer screening can be utilised in the future.

GTG also announced a partnership with the Gold Coast Private Hospital (GCPH), a member of Healthscope, to establish a Precision Medicine Clinic at the hospital.

ASX Biotech Losers in September

Code Name Price % Month Change Market Cap
RNO Rhinomed Ltd 0.036 -48.57 $10,285,909
AVE Avecho Biotech Ltd 0.004 -42.86 $10,793,168
LBT LBT Innovations 0.011 -42.11 $3,914,904
EXL Elixinol Wellness 0.007 -36.36 $4,385,379
BOT Botanix Pharma Ltd 0.120 -35.14 $170,543,618
NXS Next Science Limited 0.435 -33.08 $115,642,174
RCE Recce Pharmaceutical 0.485 -30.02 $95,463,857
4DX 4Dmedical Limited 0.450 -28.57 $155,525,102
IMU Imugene Limited 0.046 -26.98 $329,338,308
OPT Opthea Limited 0.330 -25.00 $218,726,274
BP8 Bph Global Ltd 0.002 -25.00 $2,669,460
AGH Althea Group 0.031 -24.39 $13,069,450
CHM Chimeric Therapeutic 0.028 -24.32 $14,823,283
PTX Prescient Ltd 0.056 -24.32 $45,903,228
PGC Paragon Care Limited 0.170 -22.73 $112,088,808
NSB Neuroscientific 0.070 -22.22 $10,122,341
IIQ Inoviq Ltd 0.560 -20.57 $51,530,473
ACW Actinogen Medical 0.020 -20.00 $44,326,202
ZLD Zelira Therapeutics 0.980 -18.33 $11,120,212
ZLD Zelira Therapeutics 0.980 -18.33 $11,120,212
PXS Pharmaxis Ltd 0.033 -17.50 $23,828,348
IHL Incannex Healthcare 0.068 -17.07 $107,916,704
ACR Acrux Limited 0.039 -17.02 $11,259,395
OSL Oncosil Medical 0.010 -16.67 $19,758,411
ADO Anteotech Ltd 0.026 -16.13 $57,107,503
IBX Imagion Biosys Ltd 0.014 -15.63 $17,627,849
ME1 Melodiol Glb Health 0.006 -15.38 $16,210,262
NYR Nyrada Inc. 0.022 -15.38 $3,432,191
NEU Neuren Pharmaceut. 11.060 -14.26 $1,415,004,258
NC6 Nanollose Limited 0.050 -13.79 $7,444,318
S66 Star Combo 0.095 -13.64 $12,832,883
OSX Osteopore Limited 0.061 -12.86 $9,450,036
MVP Medical Developments 0.850 -12.82 $73,359,436
PAB Patrys Limited 0.007 -12.50 $14,402,131
AHK Ark Mines Limited 0.175 -12.50 $7,900,333
SHG Singular Health 0.037 -11.90 $5,228,480
PNV Polynovo Limited 1.305 -11.82 $911,107,231
ZNO Zoono Group Ltd 0.038 -11.63 $7,217,252
VBS Vectus Biosystems 0.355 -11.25 $18,882,279
LDX Lumos Diagnostics 0.095 -9.52 $42,127,076
ARX Aroa Biosurgery 0.785 -8.72 $269,601,501
ALC Alcidion Group Ltd 0.110 -8.33 $139,747,661
ATX Amplia Therapeutics 0.081 -7.95 $15,714,469
DXB Dimerix Ltd 0.061 -7.58 $24,104,121
AT1 Atomo Diagnostics 0.026 -7.14 $16,619,260
MEM Memphasys Ltd 0.013 -7.14 $12,473,765
SDI SDI Limited 0.800 -6.98 $95,092,424
CDX Cardiex Limited 0.135 -6.90 $19,397,276
RHY Rhythm Biosciences 0.345 -6.76 $76,294,193
BXN Bioxyne Ltd 0.014 -6.67 $26,623,036
IDT IDT Australia Ltd 0.061 -6.15 $21,440,248
TRP Tissue Repair 0.250 -5.66 $11,695,089
CBL Control Bionics 0.073 -5.19 $7,475,851
OCC Orthocell Limited 0.375 -5.06 $73,988,652
VHT Volpara Health Tech 0.725 -4.61 $184,409,773
CAJ Capitol Health 0.210 -4.55 $223,819,975
IRX Inhalerx Limited 0.043 -4.44 $8,159,979
HXL Hexima 0.022 -4.35 $3,674,872
CAN Cann Group Ltd 0.120 -4.00 $51,120,490
PAA Pharmaust Limited 0.077 -2.53 $26,855,670
SOM SomnoMed Limited 0.705 -2.36 $76,556,934
PYC PYC Therapeutics 0.057 -1.72 $212,773,427
OIL Optiscan Imaging 0.073 -1.35 $60,957,979
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