Aussie health company Cogstate (ASX:CGS) was among the early winners this morning (more on that below).

And the gains were due to its proximity to a big event in the US, where the Food and Drug Administration (FDA) approved a controversial drug treatment for Alzheimer’s.

A dose of the drug, marketed as Aduhelm, is expected to cost around $56,000 for a yearly course that’s administered via intravenous fusion.

And it’s aimed at slowing the rate of decline among Alzheimer’s sufferers, rather than just addressing the disease’s symptoms.

The FDA approval marks the first of its kind since 2003, and comes amid ongoing controversy and debate in the scientific community about whether the treatment actually works.

On markets, local stocks are tracking sideways for the second straight day with no major catalysts to start the week.
 

WINNERS

Here are the best performing ASX small cap stocks at 12pm Tuesday, June 8:

Swipe or scroll to reveal the full table. Click headings to sort.

Code Name Price % Change Volume Market Cap
DOR Doriemus PLC 0.15 100 2,614,974 $4,348,734
CGS Cogstate Ltd 1.45 56 2,898,411 $158,164,206
BIR BIR Financial Ltd 0.023 44 4,826,940 $1,300,006
ANL Amani Gold Ltd 0.002 33 639,563 $18,580,495
APG Austpac Resources NL 0.002 33 41,139 $4,748,494
DTR Dateline Resources 0.11 29 283,836 $32,110,977
FGO Fargo Enterprises 0.005 25 317,425 $4,743,027
GGX Gas2Grid Limited 0.0025 25 1,755,333 $4,003,102
TSC Twenty Seven Co. Ltd 0.005 25 1,000,000 $10,642,758
YPB YPB Group Ltd 0.0025 25 3,118,571 $9,983,641
AIS Aeris Resources Ltd 0.21 20 31,659,937 $335,901,507
ACW Actinogen Medical 0.185 19 14,545,737 $257,386,575
MPA Mad Paws 0.195 15 1,697,840 $31,985,672
MTC Metalstech Ltd 0.26 14 1,736,709 $34,608,969
CAV Carnavale Resources 0.008 14 612,470 $16,661,612
CVS Cervantes Corp Ltd 0.008 14 1,745,624 $10,878,087
HWH Houston We Have Ltd 0.12 14 723,223 $39,795,810
IRD Iron Road Ltd 0.325 14 436,558 $225,799,595
HLX Helix Resources 0.041 14 36,301,731 $45,162,753
AKO Akora Resources 0.34 13 123,955 $15,367,680
CE1 Calima Energy 0.009 13 6,938,669 $82,192,447
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UK-based oil and gas explorer Doriemus (ASX:DOR) was the beneficiary of some capital markets activity commissioned by Perth-based Inyati Capital.

The company announced it will raise around $3m from sophisticated investors and eligible shareholders, to further the development of its energy assets.

Along with base fees, Inyati has applied for payment via the issue of 8m DOR units (4m shares/4m options) price at 0.1c, which marks a discount of around 15,000% to today’s 15c trading price after Doriemus shares doubled up at the opening bell. The share issue will be subject to shareholder approval.

The other big winner in morning trade —Cogstate (ASX:CGS) — gained ground via its proximity to US company Biogen.

Globally, the big biotech news of the week is the decision by US health regulators to approve Biogen’s Alzheimer’s drug — its first approval for a treatment of the disease since 2003.

Cogstate has a partnership deal with Japanese pharmaceutical company Eisai, which in turn is partnered with Biogen. Regulatory approval for Biogen’s treatment significantly sweetens the terms of Cogstate’s arrangement with Eisai. Stockhead’s Nick Sundich has more here.
 

LOSERS

Here are the best performing ASX small cap stocks at 12pm Tuesday, June 8:

Swipe or scroll to reveal the full table. Click headings to sort.

Code Name Price % Change Volume Market Cap
ALT Analytica Limited 0.002 -33 105,263 $13,198,546
CLZ Classic Min Ltd 0.0015 -25 20,650,811 $40,221,264
N1H N1 Holdings Ltd 0.05 -23 100,000 $5,301,112
T3D 333D Limited 0.002 -20 1,085 $3,442,888
TAR Taruga Minerals 0.069 -20 9,627,905 $43,470,980
CCE Carnegie Cln Energy 0.0025 -17 1,865,247 $44,107,721
AFA ASF Group Limited 0.06 -14 5,622 $55,490,840
TMS Tennant 0.025 -14 568,112 $10,595,912
CY5 Cygnus Gold Limited 0.13 -13 4,000 $16,263,015
RAN Range International 0.014 -13 333,105 $7,221,943
RTG RTG Mining Inc. 0.16 -11 119,300 $115,107,598
FPL Fremont Petroleum 0.004 -11 876,222 $21,053,306
MYG Mayfield Group Ltd 0.43 -10 10,320 $40,975,624
CNW Cirrus Net Hold Ltd 0.026 -10 1,608,432 $26,604,451
EMU EMU NL 0.035 -10 3,411,925 $16,912,636
GTE Great Western Exp. 0.135 -10 3,000 $20,429,709
DDD 3D Resources Limited 0.0045 -10 1,458,893 $19,401,860
EN1 Engage:Bdr Limited 0.0045 -10 1,238,666 $12,242,857
OEL Otto Energy Limited 0.009 -10 2,917,531 $47,950,098
SRN Surefire Rescs NL 0.018 -10 6,578,797 $21,874,208
OBM Ora Banda Mining Ltd 0.185 -10 2,563,120 $172,655,501
IMU Imugene Limited 0.335 -9 32,189,903 $1,826,432,550
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