As pot-stock aficionados know, investing in cannabis means navigating a labyrinth of regulatory developments which differ by jurisdiction.

The latest big name in healthcare to weigh in is the American Heart Association, which this week released some more sobering research — weed probably ain’t that good for the ticker.

The AHA said that cannabis has the potential to interfere with prescribed medications, and could also “trigger cardiovascular conditions” such as heart attacks.

So smoking and vaping are out, but the AHA said THC products that be consumed via oral or topical (applied to the skin) pathways “may reduce some of the potential harms”.

However, the study also highlighted some relevant findings for Australia’s CBD-only market.

Not only does cannabidiol appear to be have no heart side-effects, it may also help with reduced inflammation (a key driver of heart problems) and lower blood pressure.

The group added that there were limitations to the study in the first place — primarily because marijuana is still classified as a Schedule 1 drug by the US Drug Enforcement Agency, which means restrictions are currently in place on more detailed research into the health effects of marijuana.

Back on local markets — the cohort of 34 cannabis (or cannabis-adjacent) stocks had a reasonable fortnight by recent standards.

14 companies made a gain over the last two weeks, while four stocks traded flat and 19 were in the red.

Below is a summary of fortnightly and annual price performance for ASX-listed cannabis stocks:

Scroll or swipe to reveal table. Click headings to sort.

Code Name Price ($) 2W Tot Ret 1Y Tot Ret Market Cap
SUD SUDA PHARMACEUTICALS LTD 0.047 53.6% -49.2% $8.7M
DTZ DOTZ NANO LTD 0.19 18.8% 216.7% $59.9M
APH AUSTRALIAN PRIMARY HEMP LTD 0.15 18.5% -27.3% $11.2M
WOA WIDE OPEN AGRICULTURE LTD 0.45 15.4% 181.3% $37.0M
ZLD ZELIRA THERAPEUTICS LTD 0.06 11.3% -26.3% $57.4M
EN1 ENGAGE:BDR LTD 0.009 6.7% -77.8% $10.1M
IDT IDT AUSTRALIA LTD 0.16 6.7% 6.7% $38.3M
BOT BOTANIX PHARMACEUTICALS LTD 0.052 4.1% -78.3% $49.6M
CP1 CANNPAL ANIMAL THERAPEUTICS 0.14 3.7% -26.3% $13.0M
BDA BOD AUSTRALIA LTD 0.275 1.9% -51.3% $25.1M
AC8 AUSCANN GROUP HOLDINGS LTD 0.155 0.0% -65.9% $46.0M
EVE EVE INVESTMENTS LTD 0.006 0.0% 33.3% $22.4M
CPH CRESO PHARMA LTD 0.031 0.0% -92.6% $11.4M
RGI ROTO-GRO INTERNATIONAL LTD 0.046 0.0% -75.1% $6.9M
CAU CRONOS AUSTRALIA LTD 0.078 -1.3% -82.0% $10.0M
EXL ELIXINOL GLOBAL LTD 0.17 -2.9% -93.3% $31.8M
MDC MEDLAB CLINICAL LTD 0.14 -3.4% -73.1% $39.2M
THC THC GLOBAL GROUP LTD 0.27 -3.5% -41.5% $47.6M
ESE ESENSE-LAB LTD-CDI 0.018 -5.3% -30.8% $9.2M
IHL INCANNEX HEALTHCARE LTD 0.066 -5.7% -16.5% $50.3M
RNO RHINOMED LTD 0.075 -6.3% -76.6% $19.0M
EOF ECOFIBRE LTD 2.43 -7.3% -20.0% $800.3M
LSH LIFESPOT HEALTH LTD 0.04 -7.5% -47.1% $3.6M
LGP LITTLE GREEN PHARMA 0.335 -8.2% -25.6% $25.3M
MXC MGC PHARMACEUTICALS LTD 0.022 -8.3% -57.7% $34.8M
MMJ MMJ GROUP HOLDINGS LTD 0.097 -9.8% -64.1% $22.3M
ROO ROOTS SUSTAINABLE AGRICU-CDI 0.018 -10.0% -70.5% $2.9M
AGH ALTHEA GROUP HOLDINGS LTD 0.32 -11.1% -68.3% $74.7M
PAL PALLA PHARMA LTD 0.88 -12.0% -31.9% $110.8M
MRG MURRAY RIVER ORGANICS GROUP 0.013 -13.3% -70.5% $28.7M
SCU STEMCELL UNITED LTD 0.012 -20.0% -29.4% $7.7M
ECS ECS BOTANICS HOLDINGS LTD 0.018 -28.0% -73.9% $9.8M
CAN CANN GROUP LTD 0.455 -31.1% -77.3% $87.8M
YPB YPB GROUP LTD 0.004 -42.9% -50.0% $10.7M

There was an easy winner at the top of this week’s list, as Suda Pharmaceuticals (ASX:SDA) ripped higher by 54 per cent — the biggest two-week gain for an ASX pot stock in recent memory.

The catalyst was some positive regulatory news last week, as the company got approval to sell ZolpiMist — its mouth spray version of the insomnia drug zolpidem — into the Australian market earlier than it expected.